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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Mothers against decapentaplegic homolog 6

SKU : BHE13810372

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2187h
Alternative Names	SMAD family member 6 ; SMAD 6 ; MADH6
Categories	Elisa
Function	Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD. Binds to regulatory elements in target promoter regions.
Specificity	Natural and recombinant Human Mothers against decapentaplegic homolog 6
Subcellular Location	Nucleus
Detection Range	31.2-2000pg/mL
Entryname	SMAD6_HUMAN
Method Type	Sandwich
Platform	PF03165
Protein Name	Mothers against decapentaplegic homolog 6
Sensitivity	8.6pg/mL
Sequence	50: MFRSKRSGLV ; RRLWRSRVVP ; DREEGGSGGG ; GGGDEDGSLG ; SRAEPAPRAR ; 100: EGGGCGRSEV ; RPVAPRRPRD ; AVGQRGAQGA ; GRRRRAGGPP ; RPMSEPGAGA ; 150: GSSLLDVAEP ; GGPGWLPESD ; CETVTCCLFS ; ERDAAGAPRD ; ASDPLAGAAL ; 200: EPAGGGRSRE ; ARSRLLLLEQ ; ELKTVTYSLL ; KRLKERSLDT ; LLEAVESRGG ; 250: VPGGCVLVPR ; ADLRLGGQPA ; PPQLLLGRLF ; RWPDLQHAVE ; LKPLCGCHSF ; 300: AAAADGPTVC ; CNPYHFSRLC ; GPESPPPPYS ; RLSPRDEYKP ; LDLSDSTLSY ; 350: TETEATNSLI ; TAPGEFSDAS ; MSPDATKPSH ; WCSVAYWEHR ; TRVGRLYAVY ; 400: DQAVSIFYDL ; PQGSGFCLGQ ; LNLEQRSESV ; RRTRSKIGFG ; ILLSKEPDGV ; 450: WAYNRGEHPI ; FVNSPTLDAP ; GGRALVVRKV ; PPGYSIKVFD ; FERSGLQHAP ; 496: EPDAADGPYD ; PNSVRISFAK ; GWGPCYSRQF ; ITSCPCWLEI ; LLNNPR
Sequence Length	496
String	O43541
Sub Unit	Interacts with NEDD4L (By similarity). Interacts with WWP1 (By similarity). Interacts with RNF111 and AXIN1. Interacts with TGF-beta type I receptor superfamily members, SMAD1, HOXC8 and HOXC9. Interacts with STAMBP and PRKX.

Uniprot	O43541
Gene Name	SMAD6
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:4091
Unigene	Hs.153863

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810372	E2187h	96T	$736		Add to Cart

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