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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Membrane-bound transcription factor site-1 protease

SKU : BHE13806857

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E10827h
Alternative Names	Endopeptidase S1P ; Subtilisin/kexin-isozyme 1 ; SKI-1 ; KIAA0091 ; S1P ; SKI1
Categories	Elisa
Function	Catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu.
Specificity	Natural and recombinant Human Membrane-bound transcription factor site-1 protease
Subcellular Location	Endoplasmic reticulum membrane Single-pass type I membrane protein Golgi apparatus membrane Single-pass type I membrane protein May sort to other organelles, including lysosomal and/or endosomal compartments.
Detection Range	78-5000pg/mL
Entryname	MBTP1_HUMAN
Method Type	Sandwich
Platform	PF00082
Protein Name	Membrane-bound transcription factor site-1 protease
Sensitivity	39pg/mL
Sequence	50: MKLVNIWLLL ; LVVLLCGKKH ; LGDRLEKKSF ; EKAPCPGCSH ; LTLKVEFSST ; 100: VVEYEYIVAF ; NGYFTAKARN ; SFISSALKSS ; EVDNWRIIPR ; NNPSSDYPSD ; 150: FEVIQIKEKQ ; KAGLLTLEDH ; PNIKRVTPQR ; KVFRSLKYAE ; SDPTVPCNET ; 200: RWSQKWQSSR ; PLRRASLSLG ; SGFWHATGRH ; SSRRLLRAIP ; RQVAQTLQAD ; 250: VLWQMGYTGA ; NVRVAVFDTG ; LSEKHPHFKN ; VKERTNWTNE ; RTLDDGLGHG ; 300: TFVAGVIASM ; RECQGFAPDA ; ELHIFRVFTN ; NQVSYTSWFL ; DAFNYAILKK ; 350: IDVLNLSIGG ; PDFMDHPFVD ; KVWELTANNV ; IMVSAIGNDG ; PLYGTLNNPA ; 400: DQMDVIGVGG ; IDFEDNIARF ; SSRGMTTWEL ; PGGYGRMKPD ; IVTYGAGVRG ; 450: SGVKGGCRAL ; SGTSVASPVV ; AGAVTLLVST ; VQKRELVNPA ; SMKQALIASA ; 500: RRLPGVNMFE ; QGHGKLDLLR ; AYQILNSYKP ; QASLSPSYID ; LTECPYMWPY ; 550: CSQPIYYGGM ; PTVVNVTILN ; GMGVTGRIVD ; KPDWQPYLPQ ; NGDNIEVAFS ; 600: YSSVLWPWSG ; YLAISISVTK ; KAASWEGIAQ ; GHVMITVASP ; AETESKNGAE ; 650: QTSTVKLPIK ; VKIIPTPPRS ; KRVLWDQYHN ; LRYPPGYFPR ; DNLRMKNDPL ; 700: DWNGDHIHTN ; FRDMYQHLRS ; MGYFVEVLGA ; PFTCFDASQY ; GTLLMVDSEE ; 750: EYFPEEIAKL ; RRDVDNGLSL ; VIFSDWYNTS ; VMRKVKFYDE ; NTRQWWMPDT ; 800: GGANIPALNE ; LLSVWNMGFS ; DGLYEGEFTL ; ANHDMYYASG ; CSIAKFPEDG ; 850: VVITQTFKDQ ; GLEVLKQETA ; VVENVPILGL ; YQIPAEGGGR ; IVLYGDSNCL ; 900: DDSHRQKDCF ; WLLDALLQYT ; SYGVTPPSLS ; HSGNRQRPPS ; GAGSVTPERM ; 950: EGNHLHRYSK ; VLEAHLGDPK ; PRPLPACPRL ; SWAKPQPLNE ; TAPSNLWKHQ ; 1000: KLLSIDLDKV ; VLPNFRSNRP ; QVRPLSPGES ; GAWDIPGGIM ; PGRYNQEVGQ ; 1050: TIPVFAFLGA ; MVVLAFFVVQ ; INKAKSRPKR ; RKPRVKRPQL ; MQQVHPPKTP ; 1052: SV
Sequence Length	1052
String	Q14703

Uniprot	Q14703
Gene Name	MBTPS1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:8720
Unigene	Hs.75890

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806857	E10827h	96T	$736		Add to Cart

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