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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Melanoma antigen recognized by T-cells 1

SKU : BHE13806898

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1097h
Alternative Names	Antigen LB39-AA ; Antigen SK29-AA ; Protein Melan-A ; MART1
Categories	Elisa
Function	Involved in melanosome biogenesis by ensuring the stability of GPR143. Plays a vital role in the expression, stability, trafficking, and processing of melanocyte protein PMEL, which is critical to the formation of stage II melanosomes.
Specificity	Natural and recombinant Human Melanoma antigen recognized by T-cells 1
Subcellular Location	Endoplasmic reticulum membrane Single-pass type III membrane protein Golgi apparatus Golgi apparatus trans-Golgi network membrane Melanosome Also found in small vesicles and tubules dispersed over the entire cytoplasm. A small fraction of the protein is inserted into the membrane in an inverted orientation. Inversion of membrane topology results in the relocalization of the protein from a predominant Golgi/post-Golgi area to the endoplasmic reticulum. Melanoma cells expressing the protein with an inverted membrane topology are more effectively recognized by specific cytolytic T-lymphocytes than those expressing the protein in its native membrane orientation.
Detection Range	78-5000pg/mL
Entryname	MAR1_HUMAN
Method Type	Sandwich
Protein Name	Melanoma antigen recognized by T-cells 1
Sensitivity	31pg/mL
Sequence	50: MPREDAHFIY ; GYPKKGHGHS ; YTTAEEAAGI ; GILTVILGVL ; LLIGCWYCRR ; 100: RNGYRALMDK ; SLHVGTQCAL ; TRRCPQEGFD ; HRDSKVSLQE ; KNCEPVVPNA ; 118: PPAYEKLSAE ; QSPPPYSP
Sequence Length	118
String	Q16655
Sub Unit	Interacts with PMEL. Interacts with GPR143.

Uniprot	Q16655
Gene Name	MLANA
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:2315
Unigene	Hs.154069

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806898	E1097h	96T	$736		Add to Cart

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