Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Specificity
Natural and recombinant Human Low affinity immunoglobulin gamma Fc region receptor III-B
Subcellular Location
Cell membrane Lipid-anchor GPI-anchor Secreted Secreted after cleavage.
Detection Range
0.312-20ng/mL
Entryname
FCG3B_HUMAN
Method Type
Sandwich
Protein Name
Low affinity immunoglobulin gamma Fc region receptor III-B