Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
Specificity
Natural and recombinant Human Leukemia inhibitory factor receptor
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-927;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS) OF 52-534;IDENTIFICATION IN A COMPLEX WITH IL6ST; CNTF AND CNTFR;GLYCOSYLATION AT ASN-131; ASN-303; ASN-407 AND ASN-426;DISULFIDE BONDS;ELECTRON MICROSCOPY;SUBUNIT