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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Kininogen-1

SKU : BHE13805495

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1805h
Alternative Names	Alpha-2-thiol proteinase inhibitor ; Fitzgerald factor ; High molecular weight kininogen ; HMWK ; Williams-Fitzgerald-Flaujeac factor ; BDK ; KNG
Categories	Elisa
Function	(1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
Specificity	Natural and recombinant Human Kininogen-1
Subcellular Location	Secreted extracellular space
Detection Range	1.56-100ng/mL
Entryname	KNG1_HUMAN
Method Type	Sandwich
Platform	PF00031
Protein Name	Kininogen-1
Sensitivity	0.098ng/mL
Sequence	50: MKLITILFLC ; SRLLLSLTQE ; SQSEEIDCND ; KDLFKAVDAA ; LKKYNSQNQS ; 100: NNQFVLYRIT ; EATKTVGSDT ; FYSFKYEIKE ; GDCPVQSGKT ; WQDCEYKDAA ; 150: KAATGECTAT ; VGKRSSTKFS ; VATQTCQITP ; AEGPVVTAQY ; DCLGCVHPIS ; 200: TQSPDLEPIL ; RHGIQYFNNN ; TQHSSLFMLN ; EVKRAQRQVV ; AGLNFRITYS ; 250: IVQTNCSKEN ; FLFLTPDCKS ; LWNGDTGECT ; DNAYIDIQLR ; IASFSQNCDI ; 300: YPGKDFVQPP ; TKICVGCPRD ; IPTNSPELEE ; TLTHTITKLN ; AENNATFYFK ; 350: IDNVKKARVQ ; VVAGKKYFID ; FVARETTCSK ; ESNEELTESC ; ETKKLGQSLD ; 400: CNAEVYVVPW ; EKKIYPTVNC ; QPLGMISLMK ; RPPGFSPFRS ; SRIGEIKEET ; 450: TVSPPHTSMA ; PAQDEERDSG ; KEQGHTRRHD ; WGHEKQRKHN ; LGHGHKHERD ; 500: QGHGHQRGHG ; LGHGHEQQHG ; LGHGHKFKLD ; DDLEHQGGHV ; LDHGHKHKHG ; 550: HGHGKHKNKG ; KKNGKHNGWK ; TEHLASSSED ; STTPSAQTQE ; KTEGPTPIPS ; 600: LAKPGVTVTF ; SDFQDSDLIA ; TMMPPISPAP ; IQSDDDWIPD ; IQIDPNGLSF ; 644: NPISDFPDTT ; SPKCPGRPWK ; SVSEINPTTQ ; MKESYYFDLT ; DGLS
Sequence Length	644
String	P01042

Uniprot	P01042
Gene Name	KNG1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3827
Unigene	Hs.77741

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805495	E1805h	96T	$736		Add to Cart

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