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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Keratin, type I cytoskeletal 17

SKU : BHE13806152

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1822h
Alternative Names	39.1 ; Cytokeratin-17 ; CK-17 ; Keratin-17 ; K17
Categories	Elisa
Function	May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair.
Specificity	Natural and recombinant Human Keratin, type I cytoskeletal 17
Subcellular Location	Cytoplasm
Detection Range	0.156-10ng/mL
Entryname	K1C17_HUMAN
Method Type	Sandwich
Platform	PF00038
Protein Name	Keratin, type I cytoskeletal 17
Sensitivity	0.078ng/mL
Sequence	50: MTTSIRQFTS ; SSSIKGSSGL ; GGGSSRTSCR ; LSGGLGAGSC ; RLGSAGGLGS ; 100: TLGGSSYSSC ; YSFGSGGGYG ; SSFGGVDGLL ; AGGEKATMQN ; LNDRLASYLD ; 150: KVRALEEANT ; ELEVKIRDWY ; QRQAPGPARD ; YSQYYRTIEE ; LQNKILTATV ; 200: DNANILLQID ; NARLAADDFR ; TKFETEQALR ; LSVEADINGL ; RRVLDELTLA ; 250: RADLEMQIEN ; LKEELAYLKK ; NHEEEMNALR ; GQVGGEINVE ; MDAAPGVDLS ; 300: RILNEMRDQY ; EKMAEKNRKD ; AEDWFFSKTE ; ELNREVATNS ; ELVQSGKSEI ; 350: SELRRTMQAL ; EIELQSQLSM ; KASLEGNLAE ; TENRYCVQLS ; QIQGLIGSVE ; 400: EQLAQLRCEM ; EQQNQEYKIL ; LDVKTRLEQE ; IATYRRLLEG ; EDAHLTQYKK ; 432: EPVTTRQVRT ; IVEEVQDGKV ; ISSREQVHQT ; TR
Sequence Length	432
String	Q04695
Sub Unit	Heterodimer of a type I and a type II keratin. KRT17 associates with KRT6 isomers. Interacts with TRADD and SFN.

Uniprot	Q04695
Gene Name	KRT17
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3872
Unigene	Hs.2785

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806152	E1822h	96T	$736		Add to Cart

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