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ELISA Kit for Human Interleukin enhancer-binding factor 3

SKU : BHE13805785

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2285h
Alternative Names	Double-stranded RNA-binding protein 76 ; DRBP76 ; M-phase phosphoprotein 4 ; MPP4 ; Nuclear factor associated with dsRNA ; NFAR ; Nuclear factor of activated T-cells 90 kDa ; NF-AT-90 ; Translational control protein 80 ; TCP80 ; DRBF ; MPHOSPH4 ; NF90
Categories	Elisa
Function	May facilitate double-stranded RNA-regulated gene expression at the level of post-transcription. Can act as a translation inhibitory protein which binds to coding sequences of acid beta-glucosidase (GCase) and other mRNAs and functions at the initiation phase of GCase mRNA translation, probably by inhibiting its binding to polysomes. Can regulate protein arginine N-methyltransferase 1 activity. May regulate transcription of the IL2 gene during T-cell activation. Can promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA.
Specificity	Natural and recombinant Human Interleukin enhancer-binding factor 3
Subcellular Location	Nucleus nucleolus Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Detection Range	15.6-1000pg/mL
Entryname	ILF3_HUMAN
Method Type	Sandwich
Platform	PF00035
Protein Name	Interleukin enhancer-binding factor 3
Sensitivity	7.9pg/mL
Sequence	50: MRPMRIFVND ; DRHVMAKHSS ; VYPTQEELEA ; VQNMVSHTER ; ALKAVSDWID ; 100: EQEKGSSEQA ; ESDNMDVPPE ; DDSKEGAGEQ ; KTEHMTRTLR ; GVMRVGLVAK ; 150: GLLLKGDLDL ; ELVLLCKEKP ; TTALLDKVAD ; NLAIQLAAVT ; EDKYEILQSV ; 200: DDAAIVIKNT ; KEPPLSLTIH ; LTSPVVREEM ; EKVLAGETLS ; VNDPPDVLDR ; 250: QKCLAALASL ; RHAKWFQARA ; NGLKSCVIVI ; RVLRDLCTRV ; PTWGPLRGWP ; 300: LELLCEKSIG ; TANRPMGAGE ; ALRRVLECLA ; SGIVMPDGSG ; IYDPCEKEAT ; 350: DAIGHLDRQQ ; REDITQSAQH ; ALRLAAFGQL ; HKVLGMDPLP ; SKMPKKPKNE ; 400: NPVDYTVQIP ; PSTTYAITPM ; KRPMEEDGEE ; KSPSKKKKKI ; QKKEEKAEPP ; 450: QAMNALMRLN ; QLKPGLQYKL ; VSQTGPVHAP ; IFTMSVEVDG ; NSFEASGPSK ; 500: KTAKLHVAVK ; VLQDMGLPTG ; AEGRDSSKGE ; DSAEETEAKP ; AVVAPAPVVE ; 550: AVSTPSAAFP ; SDATAEQGPI ; LTKHGKNPVM ; ELNEKRRGLK ; YELISETGGS ; 600: HDKRFVMEVE ; VDGQKFQGAG ; SNKKVAKAYA ; ALAALEKLFP ; DTPLALDANK ; 650: KKRAPVPVRG ; GPKFAAKPHN ; PGFGMGGPMH ; NEVPPPPNLR ; GRGRGGSIRG ; 700: RGRGRGFGGA ; NHGGYMNAGA ; GYGSYGYGGN ; SATAGYSQFY ; SNGGHSGNAS ; 750: GGGGGGGGGS ; SGYGSYYQGD ; NYNSPVPPKH ; AGKKQPHGGQ ; QKPSYGSGYQ ; 800: SHQGQQQSYN ; QSPYSNYGPP ; QGKQKGYNHG ; QGSYSYSNSY ; NSPGGGGGSD ; 850: YNYESKFNYS ; GSGGRSGGNS ; YGSGGASYNP ; GSHGGYGGGS ; GGGSSYQGKQ ; 894: GGYSQSNYNS ; PGSGQNYSGP ; PSSYQSSQGG ; YGRNADHSMN ; YQYR
Sequence Length	894
String	Q12906
Sub Unit	Identified in a mRNP complex, at least composed of DHX9, DDX3X, ELAVL1, HNRNPU, IGF2BP1, ILF3, PABPC1, PCBP2, PTBP2, STAU1, STAU2, SYNCRIP and YBX1. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with FUS and SMN proteins and with PRMT1. Forms a complex with ILF2. Can also bind to PRKDC/XRCC7: this may stabilize the interaction of PRKDC/XRCC7 and the heterodimeric complex of XRCC6/KU70 and XRCC5/KU80. Forms a heteromeric complex with ZNF346 and ILF3. Found in a nuclear export complex with XPO5, ILF3, Ran and double-stranded RNA or double-stranded minihelix VA1 RNA. Found in a nuclear export complex with XPO5, RAN, ILF3, ZNF346 and double-stranded RNA. Interacts with XPO5 and ZNF346. Forms a complex with ILF2, YLPM1, KHDRBS1, RBMX, NCOA5 and PPP1CA. Interacts with EIF2C1 and EIF2C2.

Uniprot	Q12906
Gene Name	ILF3
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3609
Unigene	Hs.465885

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805785	E2285h	96T	$736		Add to Cart

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