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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Interleukin-27 subunit beta

SKU : BHE13805010

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9188h
Alternative Names	Epstein-Barr virus-induced gene 3 protein ; EBV-induced gene 3 protein ; IL27B
Categories	Elisa
Function	Cytokine with pro- and anti-inflammatory properties, that can regulate T helper cell development, suppress T-cell proliferation, stimulate cytotoxic T cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
Specificity	Natural and recombinant Human Interleukin-27 subunit beta
Subcellular Location	Secreted
Detection Range	15.6-1000pg/mL
Entryname	IL27B_HUMAN
Method Type	Sandwich
Platform	PF00041
Protein Name	Interleukin-27 subunit beta
Sensitivity	10pg/mL
Sequence	50: MTPQLLLALV ; LWASCPPCSG ; RKGPPAALTL ; PRVQCRASRY ; PIAVDCSWTL ; 100: PPAPNSTSPV ; SFIATYRLGM ; AARGHSWPCL ; QQTPTSTSCT ; ITDVQLFSMA ; 150: PYVLNVTAVH ; PWGSSSSFVP ; FITEHIIKPD ; PPEGVRLSPL ; AERQLQVQWE ; 200: PPGSWPFPEI ; FSLKYWIRYK ; RQGAARFHRV ; GPIEATSFIL ; RAVRPRARYY ; 229: VQVAAQDLTD ; YGELSDWSLP ; ATATMSLGK
Sequence Length	229
String	Q14213
Sub Unit	Heterodimer with IL27. IL-27 is an heterodimer composed IL27 and EBI3. EBI3 is also a component of the IL-12 heterodimer. Interacts with SQSTM1.

Uniprot	Q14213
Gene Name	EBI3
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:10148
Unigene	Hs.501452

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805010	E9188h	96T	$536		Add to Cart

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