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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Interferon-induced helicase C domain-containing protein 1

SKU : BHE13805413

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2803h
Alternative Names	Clinically amyopathic dermatomyositis autoantigen 140 kDa ; CADM-140 autoantigen ; Helicase with 2 CARD domains ; Helicard ; Interferon-induced with helicase C domain protein 1 ; Melanoma differentiation-associated protein 5 ; MDA-5 ; Murabutide down-regulated protein ; RIG-I-like receptor 2 ; RLR-2 ; RNA helicase-DEAD box protein 116 ; MDA5 ; RH116
Categories	Elisa
Function	RNA helicase that, through its ATP-dependent unwinding of RNA, may function to promote message degradation by specific RNases. Seems to have growth suppressive properties. Involved in innate immune defense against viruses. Upon interaction with intracellular dsRNA produced during viral replication, triggers a transduction cascade involving MAVS/IPS1, which results in the activation of NF-kappa-B, IRF3 and IRF7 and the induction of the expression of antiviral cytokines such as IFN-beta and RANTES (CCL5). ATPase activity is specifically induced by dsRNA. Essential for the production of interferons in response to picornaviruses.
Specificity	Natural and recombinant Human Interferon-induced helicase C domain-containing protein 1
Subcellular Location	Cytoplasm Nucleus May be found in the nucleus, during apoptosis.
Detection Range	78-5000pg/mL
Entryname	IFIH1_HUMAN
Method Type	Sandwich
Platform	PF00619
Protein Name	Interferon-induced helicase C domain-containing protein 1
Sensitivity	39pg/mL
Sequence	50: MSNGYSTDEN ; FRYLISCFRA ; RVKMYIQVEP ; VLDYLTFLPA ; EVKEQIQRTV ; 100: ATSGNMQAVE ; LLLSTLEKGV ; WHLGWTREFV ; EALRRTGSPL ; AARYMNPELT ; 150: DLPSPSFENA ; HDEYLQLLNL ; LQPTLVDKLL ; VRDVLDKCME ; EELLTIEDRN ; 200: RIAAAENNGN ; ESGVRELLKR ; IVQKENWFSA ; FLNVLRQTGN ; NELVQELTGS ; 250: DCSESNAEIE ; NLSQVDGPQV ; EEQLLSTTVQ ; PNLEKEVWGM ; ENNSSESSFA ; 300: DSSVVSESDT ; SLAEGSVSCL ; DESLGHNSNM ; GSDSGTMGSD ; SDEENVAARA ; 350: SPEPELQLRP ; YQMEVAQPAL ; EGKNIIICLP ; TGSGKTRVAV ; YIAKDHLDKK ; 400: KKASEPGKVI ; VLVNKVLLVE ; QLFRKEFQPF ; LKKWYRVIGL ; SGDTQLKISF ; 450: PEVVKSCDII ; ISTAQILENS ; LLNLENGEDA ; GVQLSDFSLI ; IIDECHHTNK ; 500: EAVYNNIMRH ; YLMQKLKNNR ; LKKENKPVIP ; LPQILGLTAS ; PGVGGATKQA ; 550: KAEEHILKLC ; ANLDAFTIKT ; VKENLDQLKN ; QIQEPCKKFA ; IADATREDPF ; 600: KEKLLEIMTR ; IQTYCQMSPM ; SDFGTQPYEQ ; WAIQMEKKAA ; KEGNRKERVC ; 650: AEHLRKYNEA ; LQINDTIRMI ; DAYTHLETFY ; NEEKDKKFAV ; IEDDSDEGGD ; 700: DEYCDGDEDE ; DDLKKPLKLD ; ETDRFLMTLF ; FENNKMLKRL ; AENPEYENEK ; 750: LTKLRNTIME ; QYTRTEESAR ; GIIFTKTRQS ; AYALSQWITE ; NEKFAEVGVK ; 800: AHHLIGAGHS ; SEFKPMTQNE ; QKEVISKFRT ; GKINLLIATT ; VAEEGLDIKE ; 850: CNIVIRYGLV ; TNEIAMVQAR ; GRARADESTY ; VLVAHSGSGV ; IEHETVNDFR ; 900: EKMMYKAIHC ; VQNMKPEEYA ; HKILELQMQS ; IMEKKMKTKR ; NIAKHYKNNP ; 950: SLITFLCKNC ; SVLACSGEDI ; HVIEKMHHVN ; MTPEFKELYI ; VRENKALQKK ; 1000: CADYQINGEI ; ICKCGQAWGT ; MMVHKGLDLP ; CLKIRNFVVV ; FKNNSTKKQY ; 1025: KKWVELPITF ; PNLDYSECCL ; FSDED
Sequence Length	1025
String	Q9BYX4
Sub Unit	Interacts with MAVS. Interacts with V protein of Simian virus 5, Human parainfluenza virus 2, Mumps virus, Sendai virus and Hendra virus. Binding to paramyxoviruses V proteins prevents IFN-beta induction, and the further establishment of an antiviral state. Interacts with PCBP2. Interacts with NLRC5.

Uniprot	Q9BYX4
Gene Name	IFIH1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:64135
Unigene	Hs.163173

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805413	E2803h	96T	$736		Add to Cart

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