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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Integrin-linked protein kinase

SKU : BHE13805619

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1587h
Alternative Names	59 kDa serine/threonine-protein kinase ; ILK-1 ; ILK-2 ; p59ILK ; ILK1 ; ILK2
Categories	Elisa
Function	Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
Specificity	Natural and recombinant Human Integrin-linked protein kinase
Subcellular Location	Cell junction focal adhesion Cell membrane Peripheral membrane protein Cytoplasmic side
Detection Range	0.78-50ng/mL
Entryname	ILK_HUMAN
Method Type	Sandwich
Platform	PF00023
Protein Name	Integrin-linked protein kinase
Sensitivity	0.401ng/mL
Sequence	50: MDDIFTQCRE ; GNAVAVRLWL ; DNTENDLNQG ; DDHGFSPLHW ; ACREGRSAVV ; 100: EMLIMRGARI ; NVMNRGDDTP ; LHLAASHGHR ; DIVQKLLQYK ; ADINAVNEHG ; 150: NVPLHYACFW ; GQDQVAEDLV ; ANGALVSICN ; KYGEMPVDKA ; KAPLRELLRE ; 200: RAEKMGQNLN ; RIPYKDTFWK ; GTTRTRPRNG ; TLNKHSGIDF ; KQLNFLTKLN ; 250: ENHSGELWKG ; RWQGNDIVVK ; VLKVRDWSTR ; KSRDFNEECP ; RLRIFSHPNV ; 300: LPVLGACQSP ; PAPHPTLITH ; WMPYGSLYNV ; LHEGTNFVVD ; QSQAVKFALD ; 350: MARGMAFLHT ; LEPLIPRHAL ; NSRSVMIDED ; MTARISMADV ; KFSFQCPGRM ; 400: YAPAWVAPEA ; LQKKPEDTNR ; RSADMWSFAV ; LLWELVTREV ; PFADLSNMEI ; 450: GMKVALEGLR ; PTIPPGISPH ; VCKLMKICMN ; EDPAKRPKFD ; MIVPILEKMQ ; 452: DK
Sequence Length	452
String	Q13418
Sub Unit	Interacts with cytoplasmic domain of beta 1 subunit of integrin. Could also interacts with beta 2, beta 3 and/or beta 5 subunit of integrin. Interacts (via ANK repeats) with LIMS1 and LIMS2. Interacts with parvins and probably TGFB1I1. Interacts (via ANK repeats) with EPHA1 (via SAM domain); stimulated by EFNA1 but independent of the kinase activity of EPHA1.

Uniprot	Q13418
Gene Name	ILK
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3611
Unigene	Hs.706355

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805619	E1587h	96T	$736		Add to Cart

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