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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Integrin alpha-V

SKU : BHE13805447

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0271h
Alternative Names	Vitronectin receptor subunit alpha ; CD51 ; MSK8 ; VNRA
Categories	Elisa
Function	The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Specificity	Natural and recombinant Human Integrin alpha-V
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.312-20ng/mL
Entryname	ITAV_HUMAN
Method Type	Sandwich
Platform	PF01839
Protein Name	Integrin alpha-V
Sensitivity	0.11ng/mL
Sequence	50: MAFPPRRRLR ; LGPRGLPLLL ; SGLLLPLCRA ; FNLDVDSPAE ; YSGPEGSYFG ; 100: FAVDFFVPSA ; SSRMFLLVGA ; PKANTTQPGI ; VEGGQVLKCD ; WSSTRRCQPI ; 150: EFDATGNRDY ; AKDDPLEFKS ; HQWFGASVRS ; KQDKILACAP ; LYHWRTEMKQ ; 200: EREPVGTCFL ; QDGTKTVEYA ; PCRSQDIDAD ; GQGFCQGGFS ; IDFTKADRVL ; 250: LGGPGSFYWQ ; GQLISDQVAE ; IVSKYDPNVY ; SIKYNNQLAT ; RTAQAIFDDS ; 300: YLGYSVAVGD ; FNGDGIDDFV ; SGVPRAARTL ; GMVYIYDGKN ; MSSLYNFTGE ; 350: QMAAYFGFSV ; AATDINGDDY ; ADVFIGAPLF ; MDRGSDGKLQ ; EVGQVSVSLQ ; 400: RASGDFQTTK ; LNGFEVFARF ; GSAIAPLGDL ; DQDGFNDIAI ; AAPYGGEDKK ; 450: GIVYIFNGRS ; TGLNAVPSQI ; LEGQWAARSM ; PPSFGYSMKG ; ATDIDKNGYP ; 500: DLIVGAFGVD ; RAILYRARPV ; ITVNAGLEVY ; PSILNQDNKT ; CSLPGTALKV ; 550: SCFNVRFCLK ; ADGKGVLPRK ; LNFQVELLLD ; KLKQKGAIRR ; ALFLYSRSPS ; 600: HSKNMTISRG ; GLMQCEELIA ; YLRDESEFRD ; KLTPITIFME ; YRLDYRTAAD ; 650: TTGLQPILNQ ; FTPANISRQA ; HILLDCGEDN ; VCKPKLEVSV ; DSDQKKIYIG ; 700: DDNPLTLIVK ; AQNQGEGAYE ; AELIVSIPLQ ; ADFIGVVRNN ; EALARLSCAF ; 750: KTENQTRQVV ; CDLGNPMKAG ; TQLLAGLRFS ; VHQQSEMDTS ; VKFDLQIQSS ; 800: NLFDKVSPVV ; SHKVDLAVLA ; AVEIRGVSSP ; DHVFLPIPNW ; EHKENPETEE ; 850: DVGPVVQHIY ; ELRNNGPSSF ; SKAMLHLQWP ; YKYNNNTLLY ; ILHYDIDGPM ; 900: NCTSDMEINP ; LRIKISSLQT ; TEKNDTVAGQ ; GERDHLITKR ; DLALSEGDIH ; 950: TLGCGVAQCL ; KIVCQVGRLD ; RGKSAILYVK ; SLLWTETFMN ; KENQNHSYSL ; 1000: KSSASFNVIE ; FPYKNLPIED ; ITNSTLVTTN ; VTWGIQPAPM ; PVPVWVIILA ; 1048: VLAGLLLLAV ; LVFVMYRMGF ; FKRVRPPQEE ; QEREQLQPHE ; NGEGNSET
Sequence Length	1048
String	P06756
Sub Unit	Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-V associates with either beta-1, beta-3, beta-5, beta-6 or beta-8 subunit. Interacts with HIV-1 Tat. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein and acts as a receptor for this virus (By similarity). Alpha-V/beta-6 binds to coxsackievirus A9 and coxsackievirus B1 capsid proteins and acts as a receptor for these viruses. Interacts with RAB25.

Uniprot	P06756
Gene Name	ITGAV
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3685
Unigene	Hs.436873

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805447	E0271h	96T	$736		Add to Cart

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