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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Integrin alpha-2

SKU : BHE13806017

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9122h
Alternative Names	CD49 antigen-like family member B ; Collagen receptor ; Platelet membrane glycoprotein Ia ; GPIa ; VLA-2 subunit alpha ; CD49b ; CD49B
Categories	Elisa
Function	Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Specificity	Natural and recombinant Human Integrin alpha-2
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.156-10ng/mL
Entryname	ITA2_HUMAN
Method Type	Sandwich
Platform	PF01839
Protein Name	Integrin alpha-2
Sensitivity	0.068ng/mL
Sequence	50: MGPERTGAAP ; LPLLLVLALS ; QGILNCCLAY ; NVGLPEAKIF ; SGPSSEQFGY ; 100: AVQQFINPKG ; NWLLVGSPWS ; GFPENRMGDV ; YKCPVDLSTA ; TCEKLNLQTS ; 150: TSIPNVTEMK ; TNMSLGLILT ; RNMGTGGFLT ; CGPLWAQQCG ; NQYYTTGVCS ; 200: DISPDFQLSA ; SFSPATQPCP ; SLIDVVVVCD ; ESNSIYPWDA ; VKNFLEKFVQ ; 250: GLDIGPTKTQ ; VGLIQYANNP ; RVVFNLNTYK ; TKEEMIVATS ; QTSQYGGDLT ; 300: NTFGAIQYAR ; KYAYSAASGG ; RRSATKVMVV ; VTDGESHDGS ; MLKAVIDQCN ; 350: HDNILRFGIA ; VLGYLNRNAL ; DTKNLIKEIK ; AIASIPTERY ; FFNVSDEAAL ; 400: LEKAGTLGEQ ; IFSIEGTVQG ; GDNFQMEMSQ ; VGFSADYSSQ ; NDILMLGAVG ; 450: AFGWSGTIVQ ; KTSHGHLIFP ; KQAFDQILQD ; RNHSSYLGYS ; VAAISTGEST ; 500: HFVAGAPRAN ; YTGQIVLYSV ; NENGNITVIQ ; AHRGDQIGSY ; FGSVLCSVDV ; 550: DKDTITDVLL ; VGAPMYMSDL ; KKEEGRVYLF ; TIKKGILGQH ; QFLEGPEGIE ; 600: NTRFGSAIAA ; LSDINMDGFN ; DVIVGSPLEN ; QNSGAVYIYN ; GHQGTIRTKY ; 650: SQKILGSDGA ; FRSHLQYFGR ; SLDGYGDLNG ; DSITDVSIGA ; FGQVVQLWSQ ; 700: SIADVAIEAS ; FTPEKITLVN ; KNAQIILKLC ; FSAKFRPTKQ ; NNQVAIVYNI ; 750: TLDADGFSSR ; VTSRGLFKEN ; NERCLQKNMV ; VNQAQSCPEH ; IIYIQEPSDV ; 800: VNSLDLRVDI ; SLENPGTSPA ; LEAYSETAKV ; FSIPFHKDCG ; EDGLCISDLV ; 850: LDVRQIPAAQ ; EQPFIVSNQN ; KRLTFSVTLK ; NKRESAYNTG ; IVVDFSENLF ; 900: FASFSLPVDG ; TEVTCQVAAS ; QKSVACDVGY ; PALKREQQVT ; FTINFDFNLQ ; 950: NLQNQASLSF ; QALSESQEEN ; KADNLVNLKI ; PLLYDAEIHL ; TRSTNINFYE ; 1000: ISSDGNVPSI ; VHSFEDVGPK ; FIFSLKVTTG ; SVPVSMATVI ; IHIPQYTKEK ; 1050: NPLMYLTGVQ ; TDKAGDISCN ; ADINPLKIGQ ; TSSSVSFKSE ; NFRHTKELNC ; 1100: RTASCSNVTC ; WLKDVHMKGE ; YFVNVTTRIW ; NGTFASSTFQ ; TVQLTAAAEI ; 1150: NTYNPEIYVI ; EDNTVTIPLM ; IMKPDEKAEV ; PTGVIIGSII ; AGILLLLALV ; 1181: AILWKLGFFK ; RKYEKMTKNP ; DEIDETTELS ; S
Sequence Length	1181
String	P17301
Sub Unit	Heterodimer of an alpha and a beta subunit. Alpha-2 associates with beta-1. Interacts with HPS5 and RAB21. Binds to human echoviruses 1 and 8 capsid proteins and acts as a receptor for these viruses. Interacts (via ITAG2 I-domain) with rotavirus A VP4; this interaction only occurs in rotavirus integrin-dependent strains, for which ITGA2 acts as a receptor.

Uniprot	P17301
Gene Name	ITGA2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3673
Unigene	Hs.482077

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806017	E9122h	96T	$736		Add to Cart

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