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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Insulin receptor substrate 1

SKU : BHE13805315

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1660h
Categories	Elisa
Function	May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
Specificity	Natural and recombinant Human Insulin receptor substrate 1
Detection Range	0.312-20ng/mL
Entryname	IRS1_HUMAN
Method Type	Sandwich
Platform	PF02174
Protein Name	Insulin receptor substrate 1
Sensitivity	0.168ng/mL
Sequence	50: MASPPESDGF ; SDVRKVGYLR ; KPKSMHKRFF ; VLRAASEAGG ; PARLEYYENE ; 100: KKWRHKSSAP ; KRSIPLESCF ; NINKRADSKN ; KHLVALYTRD ; EHFAIAADSE ; 150: AEQDSWYQAL ; LQLHNRAKGH ; HDGAAALGAG ; GGGGSCSGSS ; GLGEAGEDLS ; 200: YGDVPPGPAF ; KEVWQVILKP ; KGLGQTKNLI ; GIYRLCLTSK ; TISFVKLNSE ; 250: AAAVVLQLMN ; IRRCGHSENF ; FFIEVGRSAV ; TGPGEFWMQV ; DDSVVAQNMH ; 300: ETILEAMRAM ; SDEFRPRSKS ; QSSSNCSNPI ; SVPLRRHHLN ; NPPPSQVGLT ; 350: RRSRTESITA ; TSPASMVGGK ; PGSFRVRASS ; DGEGTMSRPA ; SVDGSPVSPS ; 400: TNRTHAHRHR ; GSARLHPPLN ; HSRSIPMPAS ; RCSPSATSPV ; SLSSSSTSGH ; 450: GSTSDCLFPR ; RSSASVSGSP ; SDGGFISSDE ; YGSSPCDFRS ; SFRSVTPDSL ; 500: GHTPPARGEE ; ELSNYICMGG ; KGPSTLTAPN ; GHYILSRGGN ; GHRCTPGTGL ; 550: GTSPALAGDE ; AASAADLDNR ; FRKRTHSAGT ; SPTITHQKTP ; SQSSVASIEE ; 600: YTEMMPAYPP ; GGGSGGRLPG ; HRHSAFVPTR ; SYPEEGLEMH ; PLERRGGHHR ; 650: PDSSTLHTDD ; GYMPMSPGVA ; PVPSGRKGSG ; DYMPMSPKSV ; SAPQQIINPI ; 700: RRHPQRVDPN ; GYMMMSPSGG ; CSPDIGGGPS ; SSSSSSNAVP ; SGTSYGKLWT ; 750: NGVGGHHSHV ; LPHPKPPVES ; SGGKLLPCTG ; DYMNMSPVGD ; SNTSSPSDCY ; 800: YGPEDPQHKP ; VLSYYSLPRS ; FKHTQRPGEP ; EEGARHQHLR ; LSTSSGRLLY ; 850: AATADDSSSS ; TSSDSLGGGY ; CGARLEPSLP ; HPHHQVLQPH ; LPRKVDTAAQ ; 900: TNSRLARPTR ; LSLGDPKAST ; LPRAREQQQQ ; QQPLLHPPEP ; KSPGEYVNIE ; 950: FGSDQSGYLS ; GPVAFHSSPS ; VRCPSQLQPA ; PREEETGTEE ; YMKMDLGPGR ; 1000: RAAWQESTGV ; EMGRLGPAPP ; GAASICRPTR ; AVPSSRGDYM ; TMQMSCPRQS ; 1050: YVDTSPAAPV ; SYADMRTGIA ; AEEVSLPRAT ; MAAASSSSAA ; SASPTGPQGA ; 1100: AELAAHSSLL ; GGPQGPGGMS ; AFTRVNLSPN ; RNQSAKVIRA ; DPQGCRRRHS ; 1150: SETFSSTPSA ; TRVGNTVPFG ; AGAAVGGGGG ; SSSSSEDVKR ; HSSASFENVW ; 1200: LRPGELGGAP ; KEPAKLCGAA ; GGLENGLNYI ; DLDLVKDFKQ ; CPQECTPEPQ ; 1242: PPPPPPPHQP ; LGSGESSSTR ; RSSEDLSAYA ; SISFQKQPED ; RQ
Sequence Length	1242
String	P35568
Sub Unit	Interacts with UBTF and PIK3CA (By similarity). Interacts (via phosphorylated YXXM motifs) with PIK3R1 (By similarity). Interacts with ROCK1 and FER (By similarity). Interacts (via PH domain) with PHIP (By similarity). Interacts with GRB2 (By similarity). Interacts with SOCS7. Interacts (via IRS-type PTB domain) with IGF1R and INSR (via the tyrosine-phosphorylated NPXY motif). Interacts with ALK.

Uniprot	P35568
Gene Name	IRS1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3667
Unigene	Hs.471508

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805315	E1660h	96T	$736		Add to Cart

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