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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Induced myeloid leukemia cell differentiation protein Mcl-1

SKU : BHE13807030

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E2097h
Alternative Names	Bcl-2-like protein 3 ; Bcl2-L-3 ; Bcl-2-related protein EAT/mcl1 ; mcl1/EAT ; BCL2L3
Categories	Elisa
Function	Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Specificity	Natural and recombinant Human Induced myeloid leukemia cell differentiation protein Mcl-1
Subcellular Location	Membrane Single-pass membrane protein Cytoplasm Mitochondrion Nucleus nucleoplasm Cytoplasmic, associated with mitochondria.
Detection Range	1.56-100U/mL
Entryname	MCL1_HUMAN
Method Type	Sandwich
Platform	PF00452
Protein Name	Induced myeloid leukemia cell differentiation protein Mcl-1
Sensitivity	0.39U/mL
Sequence	50: MFGLKRNAVI ; GLNLYCGGAG ; LGAGSGGATR ; PGGRLLATEK ; EASARREIGG ; 100: GEAGAVIGGS ; AGASPPSTLT ; PDSRRVARPP ; PIGAEVPDVT ; ATPARLLFFA ; 150: PTRRAAPLEE ; MEAPAADAIM ; SPEEELDGYE ; PEPLGKRPAV ; LPLLELVGES ; 200: GNNTSTDGSL ; PSTPPPAEEE ; EDELYRQSLE ; IISRYLREQA ; TGAKDTKPMG ; 250: RSGATSRKAL ; ETLRRVGDGV ; QRNHETAFQG ; MLRKLDIKNE ; DDVKSLSRVM ; 300: IHVFSDGVTN ; WGRIVTLISF ; GAFVAKHLKT ; INQESCIEPL ; AESITDVLVR ; 350:
Sequence Length	350
String	Q07820
Sub Unit	Interacts with BAD, BOK, BIK and BFM (By similarity). Interacts with PMAIP1. Isoform 1 interacts with BAX, BAK1, TPT1 and BCL2L11. Heterodimer of isoform 1 and isoform 2. Homodimers of isoform 1 or isoform 2 are not detected. Isoform 2 does not interact with pro-apoptototic BCL2-related proteins.

Uniprot	Q07820
Gene Name	MCL1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:4170
Unigene	Hs.632486

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SKU	Supplier No.	Size	Your price	Quantity
BHE13807030	E2097h	96T	$736		Add to Cart

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