JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Human Histone-lysine N-methyltransferase EZH2

SKU : BHE13803725

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E7688h
Alternative Names	ENX-1 ; Enhancer of zeste homolog 2 ; Lysine N-methyltransferase 6 ; KMT6
Categories	Elisa
Function	Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1, CDKN2A and retinoic acid target genes.
Specificity	Natural and recombinant Human Histone-lysine N-methyltransferase EZH2
Subcellular Location	Nucleus
Detection Range	0.78 -50 ng/mL
Entryname	EZH2_HUMAN
Method Type	Sandwich
Platform	PF11616
Protein Name	Histone-lysine N-methyltransferase EZH2
Sensitivity	0.24 ng/mL
Sequence	50: MGQTGKKSEK ; GPVCWRKRVK ; SEYMRLRQLK ; RFRRADEVKS ; MFSSNRQKIL ; 100: ERTEILNQEW ; KQRRIQPVHI ; LTSVSSLRGT ; RECSVTSDLD ; FPTQVIPLKT ; 150: LNAVASVPIM ; YSWSPLQQNF ; MVEDETVLHN ; IPYMGDEVLD ; QDGTFIEELI ; 200: KNYDGKVHGD ; RECGFINDEI ; FVELVNALGQ ; YNDDDDDDDG ; DDPEEREEKQ ; 250: KDLEDHRDDK ; ESRPPRKFPS ; DKIFEAISSM ; FPDKGTAEEL ; KEKYKELTEQ ; 300: QLPGALPPEC ; TPNIDGPNAK ; SVQREQSLHS ; FHTLFCRRCF ; KYDCFLHPFH ; 350: ATPNTYKRKN ; TETALDNKPC ; GPQCYQHLEG ; AKEFAAALTA ; ERIKTPPKRP ; 400: GGRRRGRLPN ; NSSRPSTPTI ; NVLESKDTDS ; DREAGTETGG ; ENNDKEEEEK ; 450: KDETSSSSEA ; NSRCQTPIKM ; KPNIEPPENV ; EWSGAEASMF ; RVLIGTYYDN ; 500: FCAIARLIGT ; KTCRQVYEFR ; VKESSIIAPA ; PAEDVDTPPR ; KKKRKHRLWA ; 550: AHCRKIQLKK ; DGSSNHVYNY ; QPCDHPRQPC ; DSSCPCVIAQ ; NFCEKFCQCS ; 600: SECQNRFPGC ; RCKAQCNTKQ ; CPCYLAVREC ; DPDLCLTCGA ; ADHWDSKNVS ; 650: CKNCSIQRGS ; KKHLLLAPSD ; VAGWGIFIKD ; PVQKNEFISE ; YCGEIISQDE ; 700: ADRRGKVYDK ; YMCSFLFNLN ; NDFVVDATRK ; GNKIRFANHS ; VNPNCYAKVM ; 746: MVNGDHRIGI ; FAKRAIQTGE ; ELFFDYRYSQ ; ADALKYVGIE ; REMEIP
Sequence Length	746
String	Q15910
Sub Unit	Binds ATRX via the SET domain (Probable). Component of the PRC2/EED-EZH2 complex, which includes EED, EZH2, SUZ12, RBBP4 and RBBP7 and possibly AEBP2. The minimum components required for methyltransferase activity of the PRC2/EED-EZH2 complex are EED, EZH2 and SUZ12. The PRC2 complex may also interact with DNMT1, DNMT3A, DNMT3B and PHF1 via the EZH2 subunit and with SIRT1 via the SUZ12 subunit. Interacts with HDAC1 and HDAC2. Interacts with PRAME.

Uniprot	Q15910
Gene Name	EZH2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:2146
Unigene	Hs.444082

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13803725	E7688h	96T	$736		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.