MOZ ; YBF2/SAS3 ; SAS2 and TIP60 protein 3 ; MYST-3 ; Monocytic leukemia zinc finger protein ; Runt-related transcription factor-binding protein 2 ; Zinc finger protein 220 ; MOZ ; MYST3 ; RUNXBP2 ; ZNF220
Categories
Elisa
Function
Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2.
Specificity
Natural and recombinant Human Histone acetyltransferase KAT6A
Subcellular Location
Nucleus Partially concentrated in subnuclear foci distinct from PML bodies, and excluded from the nucleoli.
Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. Interacts with RUNX1; phosphorylation of RUNX1 enhances the interaction. Interacts with RUNX2.