Fucosylglycoprotein 3-alpha-galactosyltransferase ; Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase ; Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase ; 2.4.1.40 ; Glycoprotein-fucosylgalactoside alpha-galactosyltransferase ; 2.4.1.37 ; Histo-blood group A transferase ; A transferase ; Histo-blood group B transferase ; B transferase ; NAGAT
Categories
Elisa
Function
This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
Specificity
Natural and recombinant Human Histo-blood group ABO system transferase
Subcellular Location
Golgi apparatus Golgi stack membrane Single-pass type II membrane protein Secreted Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.