High mobility group AT-hook protein 1 ; High mobility group protein A1 ; High mobility group protein R ; HMGIY
Categories
Elisa
Function
HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.
Specificity
Natural and recombinant Human High mobility group protein HMG-I/HMG-Y