Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Specificity
Natural and recombinant Human High affinity immunoglobulin epsilon receptor subunit alpha
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 26-201;GLYCOSYLATION AT ASN-46; ASN-67 AND ASN-191;DISULFIDE BONDS
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF 26-201;GLYCOSYLATION AT ASN-46; ASN-67; ASN-99; ASN-165 AND ASN-191;DISULFIDE BONDS
Reviews of ELISA Kit for Human High affinity immunoglobulin epsilon receptor subunit alpha