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ELISA Kit for Human Hexokinase-2

SKU : BHE13805275

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15354h
Alternative Names	Hexokinase type II ; HK II ; Muscle form hexokinase
Categories	Elisa
Specificity	Natural and recombinant Human Hexokinase-2
Subcellular Location	Mitochondrion outer membrane Its hydrophobic N-terminal sequence may be involved in membrane binding.
Entryname	HXK2_HUMAN
Platform	PF00349
Protein Name	Hexokinase-2
Sequence	50: MIASHLLAYF ; FTELNHDQVQ ; KVDQYLYHMR ; LSDETLLEIS ; KRFRKEMEKG ; 100: LGATTHPTAA ; VKMLPTFVRS ; TPDGTEHGEF ; LALDLGGTNF ; RVLWVKVTDN ; 150: GLQKVEMENQ ; IYAIPEDIMR ; GSGTQLFDHI ; AECLANFMDK ; LQIKDKKLPL ; 200: GFTFSFPCHQ ; TKLDESFLVS ; WTKGFKSSGV ; EGRDVVALIR ; KAIQRRGDFD ; 250: IDIVAVVNDT ; VGTMMTCGYD ; DHNCEIGLIV ; GTGSNACYME ; EMRHIDMVEG ; 300: DEGRMCINME ; WGAFGDDGSL ; NDIRTEFDQE ; IDMGSLNPGK ; QLFEKMISGM ; 350: YMGELVRLIL ; VKMAKEELLF ; GGKLSPELLN ; TGRFETKDIS ; DIEGEKDGIR ; 400: KAREVLMRLG ; LDPTQEDCVA ; THRICQIVST ; RSASLCAATL ; AAVLQRIKEN ; 450: KGEERLRSTI ; GVDGSVYKKH ; PHFAKRLHKT ; VRRLVPGCDV ; RFLRSEDGSG ; 500: KGAAMVTAVA ; YRLADQHRAR ; QKTLEHLQLS ; HDQLLEVKRR ; MKVEMERGLS ; 550: KETHASAPVK ; MLPTYVCATP ; DGTEKGDFLA ; LDLGGTNFRV ; LLVRVRNGKW ; 600: GGVEMHNKIY ; AIPQEVMHGT ; GDELFDHIVQ ; CIADFLEYMG ; MKGVSLPLGF ; 650: TFSFPCQQNS ; LDESILLKWT ; KGFKASGCEG ; EDVVTLLKEA ; IHRREEFDLD ; 700: VVAVVNDTVG ; TMMTCGFEDP ; HCEVGLIVGT ; GSNACYMEEM ; RNVELVEGEE ; 750: GRMCVNMEWG ; AFGDNGCLDD ; FRTEFDVAVD ; ELSLNPGKQR ; FEKMISGMYL ; 800: GEIVRNILID ; FTKRGLLFRG ; RISERLKTRG ; IFETKFLSQI ; ESDCLALLQV ; 850: RAILQHLGLE ; STCDDSIIVK ; EVCTVVARRA ; AQLCGAGMAA ; VVDRIRENRG ; 900: LDALKVTVGV ; DGTLYKLHPH ; FAKVMHETVK ; DLAPKCDVSF ; LQSEDGSGKG ; 917: AALITAVACR ; IREAGQR
Sequence Length	917
String	P52789
Sub Unit	Monomer.

Uniprot	P52789
Gene Name	HK2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3099
Unigene	Hs.406266

Reference	1. "Human hexokinase II: sequence and homology to other hexokinases." Deeb S.S., Malkki M., Laakso M. Biochem. Biophys. Res. Commun.197:68-74(1993) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Skeletal muscle. 2. "Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity." Lehto M., Huang X., Davis E.M., Le Beau M.M., Laurila E., Eriksson K.F., Bell G.I., Groop L.C. Diabetologia38:1466-1474(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT HIS-142 tissue: Blood. tissue: Muscle. tissue: Placenta. 3. Malkki M., Heikkinen S., Deeb S.S., Laakso M. Submitted (1999-05) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Skeletal muscle. 4. NIEHS SNPs program Submitted (2004-05) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS HIS-142; CYS-274; PRO-314; ILE-331; SER-387; GLN-801; LYS-844 AND ASN-881 5. Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.more... Submitted (2005-09) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Placenta. tissue: Testis. 7. "Steady state transcript levels of the type II hexokinase and type 1 glucose transporter in human tumor cell lines." Shinohara Y., Yamamoto K., Kogure K., Ichihara J., Terada H. Cancer Lett.82:27-32(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 614-739 8. "Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS] 9. "Crystal structure of human hexokinase II." Structural genomics consortium (SGC) Submitted (2006-12) to the PDB data bank [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.45 ANGSTROMS) OF 17-916 IN COMPLEX WITH GLUCOSE AND GLUCOSE-6-PHOSPHATE 10. "Amino acid substitutions in hexokinase II among patients with NIDDM." Laakso M., Malkki M., Deeb S.S. Diabetes44:330-334(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS VAL-314; CYS-353 AND GLN-775 11. "Analysis of the hexokinase II gene in subjects with insulin resistance and NIDDM and detection of a Gln142-->His substitution." Vidal-Puig A., Printz R.L., Stratton I.M., Granner D.K., Moller D.E. Diabetes44:340-346(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HIS-142 12. "Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity." Echwald S.M., Bjoerbaek C., Hansen T., Clausen J.O., Vestergaard H., Zierath J.R., Printz R.L., Granner D.K., Pedersen O. Diabetes44:347-353(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HIS-142; PHE-148; GLN-497 AND LYS-844

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