ELISA Kit for Human Hemojuvelin

Mfr.No.	E1077h
Alternative Names	Hemochromatosis type 2 protein ; RGM domain family member C ; HJV ; RGMC
Categories	Elisa
Function	Member of the repulsive guidance molecule (RGM) family. Involved in iron metabolism. Acts as a bone morphogenetic protein (BMP) coreceptor (By similarity). Enhancement of BMP signaling regulates hepcidin (HAMP) expression and iron metabolism (By similarity). May cooperate with hepcidin to restrict iron absorption in the gut. Could represent the cellular receptor for hepcidin.
Specificity	Natural and recombinant Human Hemojuvelin
Subcellular Location	Cell membrane Lipid-anchor GPI-anchor
Detection Range	0.78-50ng/mL
Entryname	RGMC_HUMAN
Method Type	Sandwich
Platform	PF06534
Protein Name	Hemojuvelin
Sensitivity	0.22ng/mL
Sequence	50: MGEPGQSPSP ; RSSHGSPPTL ; STLTLLLLLC ; GHAHSQCKIL ; RCNAEYVSST ; 100: LSLRGGGSSG ; ALRGGGGGGR ; GGGVGSGGLC ; RALRSYALCT ; RRTARTCRGD ; 150: LAFHSAVHGI ; EDLMIQHNCS ; RQGPTAPPPP ; RGPALPGAGS ; GLPAPDPCDY ; 200: EGRFSRLHGR ; PPGFLHCASF ; GDPHVRSFHH ; HFHTCRVQGA ; WPLLDNDFLF ; 250: VQATSSPMAL ; GANATATRKL ; TIIFKNMQEC ; IDQKVYQAEV ; DNLPVAFEDG ; 300: SINGGDRPGG ; SSLSIQTANP ; GNHVEIQAAY ; IGTTIIIRQT ; AGQLSFSIKV ; 350: AEDVAMAFSA ; EQDLQLCVGG ; CPPSQRLSRS ; ERNRRGAITI ; DTARRLCKEG ; 400: LPVEDAYFHS ; CVFDVLISGD ; PNFTVAAQAA ; LEDARAFLPD ; LEKLHLFPSD ; 426: AGVPLSSATL ; LAPLLSGLFV ; LWLCIQ
Sequence Length	426
String	Q6ZVN8
Sub Unit	Interacts with BMP2 and BMP4 (By similarity). Interacts with BMPR1B.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808879	E1077h	96T	$736		Add to Cart