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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Heat shock 70 kDa protein 1A/1B

SKU : BHE13805806

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0873h
Antigen	HSPA1A
Alternative Names	Heat shock 70 kDa protein 1/2 ; HSP70-1/HSP70-2 ; HSP70.1/HSP70.2 ; HSPA1 ; HSX70
Categories	Elisa
Function	In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
Specificity	Natural and recombinant Human Heat shock 70 kDa protein 1A/1B
Subcellular Location	Cytoplasm Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Detection Range	0.156-10ng/mL
Entryname	HSP71_HUMAN
Method Type	Sandwich
Platform	PF00012
Protein Name	Heat shock 70 kDa protein 1A/1B
Sensitivity	0.056ng/mL
Sequence	50: MAKAAAIGID ; LGTTYSCVGV ; FQHGKVEIIA ; NDQGNRTTPS ; YVAFTDTERL ; 100: IGDAAKNQVA ; LNPQNTVFDA ; KRLIGRKFGD ; PVVQSDMKHW ; PFQVINDGDK ; 150: PKVQVSYKGE ; TKAFYPEEIS ; SMVLTKMKEI ; AEAYLGYPVT ; NAVITVPAYF ; 200: NDSQRQATKD ; AGVIAGLNVL ; RIINEPTAAA ; IAYGLDRTGK ; GERNVLIFDL ; 250: GGGTFDVSIL ; TIDDGIFEVK ; ATAGDTHLGG ; EDFDNRLVNH ; FVEEFKRKHK ; 300: KDISQNKRAV ; RRLRTACERA ; KRTLSSSTQA ; SLEIDSLFEG ; IDFYTSITRA ; 350: RFEELCSDLF ; RSTLEPVEKA ; LRDAKLDKAQ ; IHDLVLVGGS ; TRIPKVQKLL ; 400: QDFFNGRDLN ; KSINPDEAVA ; YGAAVQAAIL ; MGDKSENVQD ; LLLLDVAPLS ; 450: LGLETAGGVM ; TALIKRNSTI ; PTKQTQIFTT ; YSDNQPGVLI ; QVYEGERAMT ; 500: KDNNLLGRFE ; LSGIPPAPRG ; VPQIEVTFDI ; DANGILNVTA ; TDKSTGKANK ; 550: ITITNDKGRL ; SKEEIERMVQ ; EAEKYKAEDE ; VQRERVSAKN ; ALESYAFNMK ; 600: SAVEDEGLKG ; KISEADKKKV ; LDKCQEVISW ; LDANTLAEKD ; EFEHKRKELE ; 641: QVCNPIISGL ; YQGAGGPGPG ; GFGAQGPKGG ; SGSGPTIEEV ; D
Sequence Length	641
String	P08107
Sub Unit	Component of a complex composed at least of CATSPER1, CATSPERB, CATSPERG and HSPA1B (By similarity). Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with TSC2. Interacts with IRAK1BP1. Interacts with TERT; the interaction occurs in the absence of the RNA component, TERC, and dissociates once the TERT complex has formed. Interacts with DNAJC7. Interacts with CHCHD3.

Uniprot	P08107
Gene Name	HSPA1A
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:3303
Unigene	Hs.274402

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805806	E0873h	96T	$536		Add to Cart

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