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Home / Assay Kits / ELISA Kits

ELISA Kit for Human GTP-binding nuclear protein Ran

SKU : BHE13809446

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15339h
Alternative Names	Androgen receptor-associated protein 24 ; GTPase Ran ; Ras-like protein TC4 ; Ras-related nuclear protein ; ARA24 ; OK/SW-cl.81
Categories	Elisa
Function	Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
Specificity	Natural and recombinant Human GTP-binding nuclear protein Ran
Subcellular Location	Nucleus Cytoplasm Melanosome Predominantly nuclear during interphase (By similarity). Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Detection Range	78-5000pg/mL
Entryname	RAN_HUMAN
Method Type	Sandwich
Platform	PF00071
Protein Name	GTP-binding nuclear protein Ran
Sensitivity	39.8pg/mL
Sequence	50: MAAQGEPQVQ ; FKLVLVGDGG ; TGKTTFVKRH ; LTGEFEKKYV ; ATLGVEVHPL ; 100: VFHTNRGPIK ; FNVWDTAGQE ; KFGGLRDGYY ; IQAQCAIIMF ; DVTSRVTYKN ; 150: VPNWHRDLVR ; VCENIPIVLC ; GNKVDIKDRK ; VKAKSIVFHR ; KKNLQYYDIS ; 200: AKSNYNFEKP ; FLWLARKLIG ; DPNLEFVAMP ; ALAPPEVVMD ; PALAAQYEHD ; 216: LEVAQTTALP ; DEDDDL
Sequence Length	216
String	P62826
Sub Unit	Monomer. Also forms a complex with CHC1 and interacts with the AR N-terminal poly-Gln region. The interaction with AR is inversely correlated with the poly-Gln length. Part of a complex consisting of RANBP9, Ran, DYRK1B and COPS5. Found in a nuclear export complex with RANBP3 and XPO1. Component of a nuclear export receptor complex composed of KPNB1, Ran, SNUPN and XPO1. Found in a trimeric export complex with SNUPN, Ran and XPO1. Interacts with RANBP10. In case of HIV-1 infection, found in a complex with HIV-1 Rev, RNAs containing a Rev response element (RRE) and XPO1. Found in a complex with HTLV-1 Rex, RANBP3 and XPO1. Interacts in its GTP-bound form with BIRC5/survivin at S and M phases of the cell cycle. Interacts with TERT; the interaction requires hydrogen peroxide-mediated phosphorylation of TERT and transports TERT to the nucleus. Interacts with MAD2L2. Interacts with RANBP10 (By similarity). Interacts with VRK1 and VRK3. Interacts with isoform 1 and isoform 2 of VRK2.

Uniprot	P62826
Gene Name	RAN
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:5901
Unigene	Hs.10842

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809446	E15339h	96T	$736		Add to Cart

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