JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Assay Kits / ELISA Kits

ELISA Kit for Human Glycogen synthase kinase-3 alpha

SKU : BHE13805220

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

EIAAB SCIENCE INC, WUHAN

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	E0767h
Alternative Names	Serine/threonine-protein kinase GSK3A ; 2.7.11.1
Categories	Elisa
Function	Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transctiption factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylation of the majority of its substrates. Contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. Regulates glycogen metabolism in liver, but not in muscle. May also mediate the development of insulin resistance by regulating activation of transcription factors. In Wnt signaling, regulates the level and transcriptional activity of nuclear CTNNB1/beta-catenin. Facilitates amyloid precursor protein (APP) processing and the generation of APP-derived amyloid plaques found in Alzheimer disease. May be involved in the regulation of replication in pancreatic beta-cells. Is necessary for the establishment of neuronal polarity and axon outgrowth.
Specificity	Natural and recombinant Human Glycogen synthase kinase-3 alpha
Detection Range	0.156-10ng/mL
Entryname	GSK3A_HUMAN
Method Type	Sandwich
Platform	PF00069
Protein Name	Glycogen synthase kinase-3 alpha
Sensitivity	0.083ng/mL
Sequence	50: MSGGGPSGGG ; PGGSGRARTS ; SFAEPGGGGG ; GGGGGPGGSA ; SGPGGTGGGK ; 100: ASVGAMGGGV ; GASSSGGGPG ; GSGGGGSGGP ; GAGTSFPPPG ; VKLGRDSGKV ; 150: TTVVATLGQG ; PERSQEVAYT ; DIKVIGNGSF ; GVVYQARLAE ; TRELVAIKKV ; 200: LQDKRFKNRE ; LQIMRKLDHC ; NIVRLRYFFY ; SSGEKKDELY ; LNLVLEYVPE ; 250: TVYRVARHFT ; KAKLTIPILY ; VKVYMYQLFR ; SLAYIHSQGV ; CHRDIKPQNL ; 300: LVDPDTAVLK ; LCDFGSAKQL ; VRGEPNVSYI ; CSRYYRAPEL ; IFGATDYTSS ; 350: IDVWSAGCVL ; AELLLGQPIF ; PGDSGVDQLV ; EIIKVLGTPT ; REQIREMNPN ; 400: YTEFKFPQIK ; AHPWTKVFKS ; RTPPEAIALC ; SSLLEYTPSS ; RLSPLEACAH ; 450: SFFDELRCLG ; TQLPNNRPLP ; PLFNFSAGEL ; SIQPSLNAIL ; IPPHLRSPAG ; 483: TTTLTPSSQA ; LTETPTSSDW ; QSTDATPTLT ; NSS
Sequence Length	483
String	P49840
Sub Unit	Monomer. Interacts with ARRB2 (By similarity). Interacts with AXIN1 and CTNNB1/beta-catenin.

Uniprot	P49840
Gene Name	GSK3A
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:2931
Unigene	Hs.466828

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHE13805220	E0767h	96T	$536		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.