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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Glyceraldehyde-3-phosphate dehydrogenase

SKU : BHE13804636

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1932h
Alternative Names	Peptidyl-cysteine S-nitrosylase GAPDH ; 2.6.99.- ; GAPD ; CDABP0047 ; OK/SW-cl.12
Categories	Elisa
Function	Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate.
Specificity	Natural and recombinant Human Glyceraldehyde-3-phosphate dehydrogenase
Subcellular Location	Cytoplasm cytosol Nucleus Cytoplasm perinuclear region Membrane Translocates to the nucleus following S-nitrosylation and interaction with SIAH1, which contains a nuclear localization signal (By similarity). Postnuclear and Perinuclear regions.
Detection Range	0.156-10ng/mL
Entryname	G3P_HUMAN
Method Type	Sandwich
Platform	PF02800
Protein Name	Glyceraldehyde-3-phosphate dehydrogenase
Sensitivity	0.1ng/mL
Sequence	50: MGKVKVGVNG ; FGRIGRLVTR ; AAFNSGKVDI ; VAINDPFIDL ; NYMVYMFQYD ; 100: STHGKFHGTV ; KAENGKLVIN ; GNPITIFQER ; DPSKIKWGDA ; GAEYVVESTG ; 150: VFTTMEKAGA ; HLQGGAKRVI ; ISAPSADAPM ; FVMGVNHEKY ; DNSLKIISNA ; 200: SCTTNCLAPL ; AKVIHDNFGI ; VEGLMTTVHA ; ITATQKTVDG ; PSGKLWRDGR ; 250: GALQNIIPAS ; TGAAKAVGKV ; IPELNGKLTG ; MAFRVPTANV ; SVVDLTCRLE ; 300: KPAKYDDIKK ; VVKQASEGPL ; KGILGYTEHQ ; VVSSDFNSDT ; HSSTFDAGAG ; 335: IALNDHFVKL ; ISWYDNEFGY ; SNRVVDLMAH ; MASKE
Sequence Length	335
String	P04406
Sub Unit	Homotetramer. Interacts with TPPP; the interaction is direct. Interacts (when S-nitrosylated) with SIAH1; leading to nuclear translocation. Interacts with RILPL1/GOSPEL, leading to prevent the interaction between GAPDH and SIAH1 and prevent nuclear translocation (By similarity). Interacts with EIF1AD, USP25, PRKCI and WARS.

Uniprot	P04406
Gene Name	GAPDH
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:2597
Unigene	Hs.544577

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804636	E1932h	96T	$736		Add to Cart

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