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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Glutaredoxin-3

SKU : BHE13804670

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0509h
Alternative Names	PKC-interacting cousin of thioredoxin ; PICOT ; PKC-theta-interacting protein ; PKCq-interacting protein ; Thioredoxin-like protein 2 ; PICOT ; TXNL2 ; HUSSY-22
Categories	Elisa
Function	Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity.
Specificity	Natural and recombinant Human Glutaredoxin-3
Subcellular Location	Cytoplasm cell cortex Cytoplasm myofibril sarcomere Z line Under the plasma membrane. After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area. In the Z line, found associated with CSRP3.
Detection Range	0.312-20ng/mL
Entryname	GLRX3_HUMAN
Method Type	Sandwich
Platform	PF00462
Protein Name	Glutaredoxin-3
Sensitivity	0.12ng/mL
Sequence	50: MAAGAAEAAV ; AAVEEVGSAG ; QFEELLRLKA ; KSLLVVHFWA ; PWAPQCAQMN ; 100: EVMAELAKEL ; PQVSFVKLEA ; EGVPEVSEKY ; EISSVPTFLF ; FKNSQKIDRL ; 150: DGAHAPELTK ; KVQRHASSGS ; FLPSANEHLK ; EDLNLRLKKL ; THAAPCMLFM ; 200: KGTPQEPRCG ; FSKQMVEILH ; KHNIQFSSFD ; IFSDEEVRQG ; LKAYSSWPTY ; 250: PQLYVSGELI ; GGLDIIKELE ; ASEELDTICP ; KAPKLEERLK ; VLTNKASVML ; 300: FMKGNKQEAK ; CGFSKQILEI ; LNSTGVEYET ; FDILEDEEVR ; QGLKAYSNWP ; 335: TYPQLYVKGE ; LVGGLDIVKE ; LKENGELLPI ; LRGEN
Sequence Length	335
String	O76003
Sub Unit	Monomer and homodimer; the homodimer is probably linked by 2 2Fe-2S clusters that may serve as a redox sensor. The monomer interacts with other proteins. Interacts (via N-terminus) with PRKCQ/PKC-theta. Interacts (via C-terminus) with CSRP3 (By similarity). Interacts with CSRP2.

Uniprot	O76003
Gene Name	GLRX3
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:10539
Unigene	Hs.42644

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804670	E0509h	96T	$736		Add to Cart

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