ELISA Kit for Human Glutaminyl-peptide cyclotransferase

Mfr.No.	E2087h
Alternative Names	Glutaminyl cyclase ; QC ; Glutaminyl-tRNA cyclotransferase ; Glutamyl cyclase ; EC
Categories	Elisa
Function	Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.
Specificity	Natural and recombinant Human Glutaminyl-peptide cyclotransferase
Subcellular Location	Secreted
Detection Range	0.156-10ng/mL
Entryname	QPCT_HUMAN
Method Type	Sandwich
Platform	PF04389
Protein Name	Glutaminyl-peptide cyclotransferase
Sensitivity	0.056ng/mL
Sequence	50: MAGGRHRRVV ; GTLHLLLLVA ; ALPWASRGVS ; PSASAWPEEK ; NYHQPAILNS ; 100: SALRQIAEGT ; SISEMWQNDL ; QPLLIERYPG ; SPGSYAARQH ; IMQRIQRLQA ; 150: DWVLEIDTFL ; SQTPYGYRSF ; SNIISTLNPT ; AKRHLVLACH ; YDSKYFSHWN ; 200: NRVFVGATDS ; AVPCAMMLEL ; ARALDKKLLS ; LKTVSDSKPD ; LSLQLIFFDG ; 250: EEAFLHWSPQ ; DSLYGSRHLA ; AKMASTPHPP ; GARGTSQLHG ; MDLLVLLDLI ; 300: GAPNPTFPNF ; FPNSARWFER ; LQAIEHELHE ; LGLLKDHSLE ; GRYFQNYSYG ; 350: GVIQDDHIPF ; LRRGVPVLHL ; IPSPFPEVWH ; TMDDNEENLD ; ESTIDNLNKI ; 361: LQVFVLEYLH ; L
Sequence Length	361
String	Q16769

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810168	E2087h	96T	$736		Add to Cart