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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Forkhead box protein O3

SKU : BHE13803965

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0762h
Alternative Names	AF6q21 protein ; Forkhead in rhabdomyosarcoma-like 1 ; FKHRL1 ; FOXO3A
Categories	Elisa
Function	Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'.
Specificity	Natural and recombinant Human Forkhead box protein O3
Subcellular Location	Cytoplasm cytosol Nucleus Translocates to the nucleus upon oxidative stress and in the absence of survival factors.
Detection Range	0.312-20ng/mL
Entryname	FOXO3_HUMAN
Method Type	Sandwich
Platform	PF00250
Protein Name	Forkhead box protein O3
Sensitivity	0.1ng/mL
Sequence	50: MAEAPASPAP ; LSPLEVELDP ; EFEPQSRPRS ; CTWPLQRPEL ; QASPAKPSGE ; 100: TAADSMIPEE ; EDDEDDEDGG ; GRAGSAMAIG ; GGGGSGTLGS ; GLLLEDSARV ; 150: LAPGGQDPGS ; GPATAAGGLS ; GGTQALLQPQ ; QPLPPPQPGA ; AGGSGQPRKC ; 200: SSRRNAWGNL ; SYADLITRAI ; ESSPDKRLTL ; SQIYEWMVRC ; VPYFKDKGDS ; 250: NSSAGWKNSI ; RHNLSLHSRF ; MRVQNEGTGK ; SSWWIINPDG ; GKSGKAPRRR ; 300: AVSMDNSNKY ; TKSRGRAAKK ; KAALQTAPES ; ADDSPSQLSK ; WPGSPTSRSS ; 350: DELDAWTDFR ; SRTNSNASTV ; SGRLSPIMAS ; TELDEVQDDD ; APLSPMLYSS ; 400: SASLSPSVSK ; PCTVELPRLT ; DMAGTMNLND ; GLTENLMDDL ; LDNITLPPSQ ; 450: PSPTGGLMQR ; SSSFPYTTKG ; SGLGSPTSSF ; NSTVFGPSSL ; NSLRQSPMQT ; 500: IQENKPATFS ; SMSHYGNQTL ; QDLLTSDSLS ; HSDVMMTQSD ; PLMSQASTAV ; 550: SAQNSRRNVM ; LRNDPMMSFA ; AQPNQGSLVN ; QNLLHHQHQT ; QGALGGSRAL ; 600: SNSVSNMGLS ; ESSSLGSAKH ; QQQSPVSQSM ; QTLSDSLSGS ; SLYSTSANLP ; 650: VMGHEKFPSD ; LDLDMFNGSL ; ECDMESIIRS ; ELMDADGLDF ; NFDSLISTQN ; 673: VVGLNVGNFT ; GAKQASSQSW ; VPG
Sequence Length	673
String	O43524
Sub Unit	Interacts with YWHAB/14-3-3-beta and YWHAZ/14-3-3-zeta, which are required for cytosolic sequestration. Upon oxidative stress, interacts with STK4/MST1, which disrupts interaction with YWHAB/14-3-3-beta and leads to nuclear translocation. Interacts with PIM1.

Uniprot	O43524
Gene Name	FOXO3
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:2309
Unigene	Hs.220950

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803965	E0762h	96T	$736		Add to Cart

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