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ELISA Kit for Human Filamin-B

SKU : BHE13804061

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11396h
Alternative Names	ABP-278 ; ABP-280 homolog ; Actin-binding-like protein ; Beta-filamin ; Filamin homolog 1 ; Fh1 ; Filamin-3 ; Thyroid autoantigen ; Truncated actin-binding protein ; Truncated ABP ; FLN1L ; FLN3 ; TABP ; TAP
Categories	Elisa
Function	Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Various interactions and localizations of isoforms affect myotube morphology and myogenesis. Isoform 6 accelerates muscle differentiation in vitro.
Specificity	Natural and recombinant Human Filamin-B
Subcellular Location	Isoform 6 Cytoplasm cytoskeleton Polarized at the periphery of myotubes.
Detection Range	31.2-2000pg/mL
Entryname	FLNB_HUMAN
Method Type	Sandwich
Platform	PF00307
Protein Name	Filamin-B
Sensitivity	7.9pg/mL
Sequence	50: MPVTEKDLAE ; DAPWKKIQQN ; TFTRWCNEHL ; KCVNKRIGNL ; QTDLSDGLRL ; 100: IALLEVLSQK ; RMYRKYHQRP ; TFRQMQLENV ; SVALEFLDRE ; SIKLVSIDSK ; 150: AIVDGNLKLI ; LGLVWTLILH ; YSISMPVWED ; EGDDDAKKQT ; PKQRLLGWIQ ; 200: NKIPYLPITN ; FNQNWQDGKA ; LGALVDSCAP ; GLCPDWESWD ; PQKPVDNARE ; 250: AMQQADDWLG ; VPQVITPEEI ; IHPDVDEHSV ; MTYLSQFPKA ; KLKPGAPLKP ; 300: KLNPKKARAY ; GRGIEPTGNM ; VKQPAKFTVD ; TISAGQGDVM ; VFVEDPEGNK ; 350: EEAQVTPDSD ; KNKTYSVEYL ; PKVTGLHKVT ; VLFAGQHISK ; SPFEVSVDKA ; 400: QGDASKVTAK ; GPGLEAVGNI ; ANKPTYFDIY ; TAGAGVGDIG ; VEVEDPQGKN ; 450: TVELLVEDKG ; NQVYRCVYKP ; MQPGPHVVKI ; FFAGDTIPKS ; PFVVQVGEAC ; 500: NPNACRASGR ; GLQPKGVRIR ; ETTDFKVDTK ; AAGSGELGVT ; MKGPKGLEEL ; 550: VKQKDFLDGV ; YAFEYYPSTP ; GRYSIAITWG ; GHHIPKSPFE ; VQVGPEAGMQ ; 600: KVRAWGPGLH ; GGIVGRSADF ; VVESIGSEVG ; SLGFAIEGPS ; QAKIEYNDQN ; 650: DGSCDVKYWP ; KEPGEYAVHI ; MCDDEDIKDS ; PYMAFIHPAT ; GGYNPDLVRA ; 700: YGPGLEKSGC ; IVNNLAEFTV ; DPKDAGKAPL ; KIFAQDGEGQ ; RIDIQMKNRM ; 750: DGTYACSYTP ; VKAIKHTIAV ; VWGGVNIPHS ; PYRVNIGQGS ; HPQKVKVFGP ; 800: GVERSGLKAN ; EPTHFTVDCT ; EAGEGDVSVG ; IKCDARVLSE ; DEEDVDFDII ; 850: HNANDTFTVK ; YVPPAAGRYT ; IKVLFASQEI ; PASPFRVKVD ; PSHDASKVKA ; 900: EGPGLSKAGV ; ENGKPTHFTV ; YTKGAGKAPL ; NVQFNSPLPG ; DAVKDLDIID ; 950: NYDYSHTVKY ; TPTQQGNMQV ; LVTYGGDPIP ; KSPFTVGVAA ; PLDLSKIKLN ; 1000: GLENRVEVGK ; DQEFTVDTRG ; AGGQGKLDVT ; ILSPSRKVVP ; CLVTPVTGRE ; 1050: NSTAKFIPRE ; EGLYAVDVTY ; DGHPVPGSPY ; TVEASLPPDP ; SKVKAHGPGL ; 1100: EGGLVGKPAE ; FTIDTKGAGT ; GGLGLTVEGP ; CEAKIECSDN ; GDGTCSVSYL ; 1150: PTKPGEYFVN ; ILFEEVHIPG ; SPFKADIEMP ; FDPSKVVASG ; PGLEHGKVGE ; 1200: AGLLSVDCSE ; AGPGALGLEA ; VSDSGTKAEV ; SIQNNKDGTY ; AVTYVPLTAG ; 1250: MYTLTMKYGG ; ELVPHFPARV ; KVEPAVDTSR ; IKVFGPGIEG ; KDVFREATTD ; 1300: FTVDSRPLTQ ; VGGDHIKAHI ; ANPSGASTEC ; FVTDNADGTY ; QVEYTPFEKG ; 1350: LHVVEVTYDD ; VPIPNSPFKV ; AVTEGCQPSR ; VQAQGPGLKE ; AFTNKPNVFT ; 1400: VVTRGAGIGG ; LGITVEGPSE ; SKINCRDNKD ; GSCSAEYIPF ; APGDYDVNIT ; 1450: YGGAHIPGSP ; FRVPVKDVVD ; PSKVKIAGPG ; LGSGVRARVL ; QSFTVDSSKA ; 1500: GLAPLEVRVL ; GPRGLVEPVN ; VVDNGDGTHT ; VTYTPSQEGP ; YMVSVKYADE ; 1550: EIPRSPFKVK ; VLPTYDASKV ; TASGPGLSSY ; GVPASLPVDF ; AIDARDAGEG ; 1600: LLAVQITDQE ; GKPKRAIVHD ; NKDGTYAVTY ; IPDKTGRYMI ; GVTYGGDDIP ; 1650: LSPYRIRATQ ; TGDASKCLAT ; GPGIASTVKT ; GEEVGFVVDA ; KTAGKGKVTC ; 1700: TVLTPDGTEA ; EADVIENEDG ; TYDIFYTAAK ; PGTYVIYVRF ; GGVDIPNSPF ; 1750: TVMATDGEVT ; AVEEAPVNAC ; PPGFRPWVTE ; EAYVPVSDMN ; GLGFKPFDLV ; 1800: IPFAVRKGEI ; TGEVHMPSGK ; TATPEIVDNK ; DGTVTVRYAP ; TEVGLHEMHI ; 1850: KYMGSHIPES ; PLQFYVNYPN ; SGSVSAYGPG ; LVYGVANKTA ; TFTIVTEDAG ; 1900: EGGLDLAIEG ; PSKAEISCID ; NKDGTCTVTY ; LPTLPGDYSI ; LVKYNDKHIP ; 1950: GSPFTAKITD ; DSRRCSQVKL ; GSAADFLLDI ; SETDLSSLTA ; SIKAPSGRDE ; 2000: PCLLKRLPNN ; HIGISFIPRE ; VGEHLVSIKK ; NGNHVANSPV ; SIMVVQSEIG ; 2050: DARRAKVYGR ; GLSEGRTFEM ; SDFIVDTRDA ; GYGGISLAVE ; GPSKVDIQTE ; 2100: DLEDGTCKVS ; YFPTVPGVYI ; VSTKFADEHV ; PGSPFTVKIS ; GEGRVKESIT ; 2150: RTSRAPSVAT ; VGSICDLNLK ; IPEINSSDMS ; AHVTSPSGRV ; TEAEIVPMGK ; 2200: NSHCVRFVPQ ; EMGVHTVSVK ; YRGQHVTGSP ; FQFTVGPLGE ; GGAHKVRAGG ; 2250: PGLERGEAGV ; PAEFSIWTRE ; AGAGGLSIAV ; EGPSKAEITF ; DDHKNGSCGV ; 2300: SYIAQEPGNY ; EVSIKFNDEH ; IPESPYLVPV ; IAPSDDARRL ; TVMSLQESGL ; 2350: KVNQPASFAI ; RLNGAKGKID ; AKVHSPSGAV ; EECHVSELEP ; DKYAVRFIPH ; 2400: ENGVHTIDVK ; FNGSHVVGSP ; FKVRVGEPGQ ; AGNPALVSAY ; GTGLEGGTTG ; 2450: IQSEFFINTT ; RAGPGTLSVT ; IEGPSKVKMD ; CQETPEGYKV ; MYTPMAPGNY ; 2500: LISVKYGGPN ; HIVGSPFKAK ; VTGQRLVSPG ; SANETSSILV ; ESVTRSSTET ; 2550: CYSAIPKASS ; DASKVTSKGA ; GLSKAFVGQK ; SSFLVDCSKA ; GSNMLLIGVH ; 2600: GPTTPCEEVS ; MKHVGNQQYN ; VTYVVKERGD ; YVLAVKWGEE ; HIPGSPFHVT ; 2602: VP
Sequence Length	2602
String	O75369
Sub Unit	Homodimer. Isoform 1 interacts with FBLP1, FLNA, FLNC, GP1BA, INPPL1, ITGB1A, PSEN1 and PSEN2. Isoform 3 interacts with ITGB1A, ITGB1D, ITGB3 and ITGB6. Interacts with MYOT and MYOZ1. Interacts with HBV capsid protein.

Uniprot	O75369
Gene Name	FLNB
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:2317
Unigene	Hs.476448

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BHE13804061	E11396h	96T	$736		Add to Cart

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