Collagen/fibrinogen domain-containing lectin 3 p35 ; Collagen/fibrinogen domain-containing protein 3 ; Hakata antigen ; FCNH ; HAKA1
Categories
Elisa
Function
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Has affinity with GalNAc, GlcNAc, D-fucose, as mono/oligosaccharide and lipopolysaccharides from S.typhimurium and S.minnesota.
Specificity
Natural and recombinant Human Ficolin-3
Subcellular Location
Secreted Found in blood plasma, bronchus, alveolus and bile duct.
Homopolymer; disulfide-linked. May be an octadecamer consisting of an elementary trimer unit. Does not interact with fibronectin, elastin or zymosan. Interacts with MASP1 and MASP2.