ELISA Kit for Human Ferritin, mitochondrial

Mfr.No.	E1305h
Categories	Elisa
Function	Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
Specificity	Natural and recombinant Human Ferritin, mitochondrial
Subcellular Location	Mitochondrion
Detection Range	0.625-40ng/mL
Entryname	FTMT_HUMAN
Method Type	Sandwich
Platform	PF00210
Protein Name	Ferritin, mitochondrial
Sensitivity	0.32ng/mL
Sequence	50: MLSCFRLLSR ; HISPSLASLR ; PVRCCFALPL ; RWAPGRPLDP ; RQIAPRRPLA ; 100: AAASSRDPTG ; PAAGPSRVRQ ; NFHPDSEAAI ; NRQINLELYA ; SYVYLSMAYY ; 150: FSRDDVALNN ; FSRYFLHQSR ; EETEHAEKLM ; RLQNQRGGRI ; RLQDIKKPEQ ; 200: DDWESGLHAM ; ECALLLEKNV ; NQSLLELHAL ; ASDKGDPHLC ; DFLETYYLNE ; 242: QVKSIKELGD ; HVHNLVKMGA ; PDAGLAEYLF ; DTHTLGNENK ; QN
Sequence Length	242
String	Q8N4E7
Sub Unit	Homooligomer of 24 subunits. The functional molecule is roughly spherical and contains a central cavity into which the polymeric mineral iron core is deposited.

Reference	1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Brain. 2. "A human mitochondrial ferritin encoded by an intronless gene." Levi S., Corsi B., Bosisio M., Invernizzi R., Volz A., Sanford D., Arosio P., Drysdale J. J. Biol. Chem.276:24437-24440(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY 3. "Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala." Langlois d'Estaintot B., Santambrogio P., Granier T., Gallois B., Chevalier J.M., Precigoux G., Levi S., Arosio P. J. Mol. Biol.340:277-293(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.38 ANGSTROMS) OF 61-242;FUNCTION;MUTAGENESIS OF SER-204

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804457	E1305h	96T	$736		Add to Cart