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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Epidermal growth factor receptor

SKU : BHE13803788

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0757h
Alternative Names	Proto-oncogene c-ErbB-1 ; Receptor tyrosine-protein kinase erbB-1 ; ERBB ; ERBB1 ; HER1
Categories	Elisa
Function	Isoform 2 may act as an antagonist of EGF action.
Specificity	Natural and recombinant Human Epidermal growth factor receptor
Subcellular Location	Isoform 2 Secreted
Detection Range	78-5000pg/mL
Entryname	EGFR_HUMAN
Method Type	Sandwich
Platform	PF00757
Protein Name	Epidermal growth factor receptor
Sensitivity	31pg/mL
Sequence	50: MRPSGTAGAA ; LLALLAALCP ; ASRALEEKKV ; CQGTSNKLTQ ; LGTFEDHFLS ; 100: LQRMFNNCEV ; VLGNLEITYV ; QRNYDLSFLK ; TIQEVAGYVL ; IALNTVERIP ; 150: LENLQIIRGN ; MYYENSYALA ; VLSNYDANKT ; GLKELPMRNL ; QEILHGAVRF ; 200: SNNPALCNVE ; SIQWRDIVSS ; DFLSNMSMDF ; QNHLGSCQKC ; DPSCPNGSCW ; 250: GAGEENCQKL ; TKIICAQQCS ; GRCRGKSPSD ; CCHNQCAAGC ; TGPRESDCLV ; 300: CRKFRDEATC ; KDTCPPLMLY ; NPTTYQMDVN ; PEGKYSFGAT ; CVKKCPRNYV ; 350: VTDHGSCVRA ; CGADSYEMEE ; DGVRKCKKCE ; GPCRKVCNGI ; GIGEFKDSLS ; 400: INATNIKHFK ; NCTSISGDLH ; ILPVAFRGDS ; FTHTPPLDPQ ; ELDILKTVKE ; 450: ITGFLLIQAW ; PENRTDLHAF ; ENLEIIRGRT ; KQHGQFSLAV ; VSLNITSLGL ; 500: RSLKEISDGD ; VIISGNKNLC ; YANTINWKKL ; FGTSGQKTKI ; ISNRGENSCK ; 550: ATGQVCHALC ; SPEGCWGPEP ; RDCVSCRNVS ; RGRECVDKCN ; LLEGEPREFV ; 600: ENSECIQCHP ; ECLPQAMNIT ; CTGRGPDNCI ; QCAHYIDGPH ; CVKTCPAGVM ; 650: GENNTLVWKY ; ADAGHVCHLC ; HPNCTYGCTG ; PGLEGCPTNG ; PKIPSIATGM ; 700: VGALLLLLVV ; ALGIGLFMRR ; RHIVRKRTLR ; RLLQERELVE ; PLTPSGEAPN ; 750: QALLRILKET ; EFKKIKVLGS ; GAFGTVYKGL ; WIPEGEKVKI ; PVAIKELREA ; 800: TSPKANKEIL ; DEAYVMASVD ; NPHVCRLLGI ; CLTSTVQLIT ; QLMPFGCLLD ; 850: YVREHKDNIG ; SQYLLNWCVQ ; IAKGMNYLED ; RRLVHRDLAA ; RNVLVKTPQH ; 900: VKITDFGLAK ; LLGAEEKEYH ; AEGGKVPIKW ; MALESILHRI ; YTHQSDVWSY ; 950: GVTVWELMTF ; GSKPYDGIPA ; SEISSILEKG ; ERLPQPPICT ; IDVYMIMVKC ; 1000: WMIDADSRPK ; FRELIIEFSK ; MARDPQRYLV ; IQGDERMHLP ; SPTDSNFYRA ; 1050: LMDEEDMDDV ; VDADEYLIPQ ; QGFFSSPSTS ; RTPLLSSLSA ; TSNNSTVACI ; 1100: DRNGLQSCPI ; KEDSFLQRYS ; SDPTGALTED ; SIDDTFLPVP ; EYINQSVPKR ; 1150: PAGSVQNPVY ; HNQPLNPAPS ; RDPHYQDPHS ; TAVGNPEYLN ; TVQPTCVNST ; 1200: FDSPAHWAQK ; GSHQISLDNP ; DYQQDFFPKE ; AKPNGIFKGS ; TAENAEYLRV ; 1210: APQSSEFIGA ;
Sequence Length	1210
String	P00533
Sub Unit	EGF binding triggers dimerization of the receptor and promotes autophosphorylation. The activate receptor dimer binds one EGF molecule. Heterodimer with ERBB2. Interacts with ERRFI1. Interaction with ERRFI1 inhibits dimerization of the kinase domain and autophosphorylation. Binds RIPK1. Interacts (via autophosphorylated C-terminal tail) with CBL. Part of a complex with ERBB2 and either PIK3C2A or PIK3C2B. Interacts (autophosphorylated form) with PIK3C2B; the interaction may be indirect. Interacts with PELP1. Binds MUC1. Interacts with AP2M1. Interacts with GAB2. Interacts with COPG, upon EGF treatment; interaction is essential for regulation of EGF-dependent nuclear transport of EGFR by retrograde trafficking from the Golgi to the ER. Interacts with TNK2; this interaction is dependent on EGF stimulation and kinase activity of EGFR. Interacts with FER.

Uniprot	P00533
Gene Name	EGFR
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:1956
Unigene	Hs.488293

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803788	E0757h	96T	$536		Add to Cart

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