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Home / Assay Kits / ELISA Kits

ELISA Kit for Human E3 ubiquitin-protein ligase TRIM63

SKU : BHE13811663

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E5054h
Alternative Names	Iris RING finger protein ; Muscle-specific RING finger protein 1 ; MuRF-1 ; RING finger protein 28 ; RING-type E3 ubiquitin transferase TRIM63 ; Striated muscle RING zinc finger protein ; Tripartite motif-containing protein 63 ; IRF ; MURF1 ; RNF28 ; SMRZ
Categories	Elisa
Function	E3 ubiquitin ligase. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.
Specificity	Natural and recombinant Human E3 ubiquitin-protein ligase TRIM63
Subcellular Location	Cytoplasm Nucleus Localizes to the M- and Z-lines in skeletal muscle. Colocalizes with TNNI3 in myocytes.
Entryname	TRI63_HUMAN
Platform	PF00643
Protein Name	E3 ubiquitin-protein ligase TRIM63
Sequence	50: MDYKSSLIQD ; GNPMENLEKQ ; LICPICLEMF ; TKPVVILPCQ ; HNLCRKCAND ; 100: IFQAANPYWT ; SRGSSVSMSG ; GRFRCPTCRH ; EVIMDRHGVY ; GLQRNLLVEN ; 150: IIDIYKQECS ; SRPLQKGSHP ; MCKEHEDEKI ; NIYCLTCEVP ; TCSMCKVFGI ; 200: HKACEVAPLQ ; SVFQGQKTEL ; NNCISMLVAG ; NDRVQTIITQ ; LEDSRRVTKE ; 250: NSHQVKEELS ; QKFDTLYAIL ; DEKKSELLQR ; ITQEQEKKLS ; FIEALIQQYQ ; 300: EQLDKSTKLV ; ETAIQSLDEP ; GGATFLLTAK ; QLIKSIVEAS ; KGCQLGKTEQ ; 350: GFENMDFFTL ; DLEHIADALR ; AIDFGTDEEE ; EEFIEEEDQE ; EEESTEGKEE ; 353: GHQ
Sequence Length	353
String	Q969Q1
Sub Unit	Homooligomer and heterooligomer. Interacts with SUMO2, titin/TTN and GMEB1. Interacts with TRIM54 and probably with TRIM55 and TNNI3. Forms a ternary complex with GNB2L1 and PRKCE.

Uniprot	Q969Q1
Gene Name	TRIM63
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:84676
Unigene	Hs.279709

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811663	E5054h	96T	$736		Add to Cart

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