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ELISA Kit for Human Deleted in malignant brain tumors 1 protein

SKU : BHE13803176

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15081h
Alternative Names	Glycoprotein 340 ; Gp-340 ; Hensin ; Salivary agglutinin ; SAG ; Surfactant pulmonary-associated D-binding protein ; GP340
Categories	Elisa
Function	May be considered as a candidate tumor suppressor gene for brain, lung, esophageal, gastric, and colorectal cancers. May play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. May function as a binding protein in saliva for the regulation of taste sensation. Binds to HIV-1 envelope protein and has been shown to both inhibit and facilitate viral transmission. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell.
Specificity	Natural and recombinant Human Deleted in malignant brain tumors 1 protein
Subcellular Location	Secreted Some isoforms may be membrane-bound. Localized to the lumenal aspect of crypt cells in the small intestine. In the colon, seen in the lumenal aspect of surface epithelial cells. Formed in the ducts of von Ebner gland, and released into the fluid bathing the taste buds contained in the taste papillae.
Detection Range	78-5000pg/mL
Entryname	DMBT1_HUMAN
Method Type	Sandwich
Platform	PF00431
Protein Name	Deleted in malignant brain tumors 1 protein
Sensitivity	39pg/mL
Sequence	50: MGISTVILEM ; CLLWGQVLST ; GGWIPRTTDY ; ASLIPSEVPL ; DPTVAEGSPF ; 100: PSESTLESTV ; AEGSPISLES ; TLESTVAEGS ; LIPSESTLES ; TVAEGSDSGL ; 150: ALRLVNGDGR ; CQGRVEILYR ; GSWGTVCDDS ; WDTNDANVVC ; RQLGCGWAMS ; 200: APGNAWFGQG ; SGPIALDDVR ; CSGHESYLWS ; CPHNGWLSHN ; CGHGEDAGVI ; 250: CSAAQPQSTL ; RPESWPVRIS ; PPVPTEGSES ; SLALRLVNGG ; DRCRGRVEVL ; 300: YRGSWGTVCD ; DYWDTNDANV ; VCRQLGCGWA ; MSAPGNAQFG ; QGSGPIVLDD ; 350: VRCSGHESYL ; WSCPHNGWLT ; HNCGHSEDAG ; VICSAPQSRP ; TPSPDTWPTS ; 400: HASTAGPESS ; LALRLVNGGD ; RCQGRVEVLY ; RGSWGTVCDD ; SWDTSDANVV ; 450: CRQLGCGWAT ; SAPGNARFGQ ; GSGPIVLDDV ; RCSGYESYLW ; SCPHNGWLSH ; 500: NCQHSEDAGV ; ICSAAHSWST ; PSPDTLPTIT ; LPASTVGSES ; SLALRLVNGG ; 550: DRCQGRVEVL ; YRGSWGTVCD ; DSWDTNDANV ; VCRQLGCGWA ; MLAPGNARFG ; 600: QGSGPIVLDD ; VRCSGNESYL ; WSCPHNGWLS ; HNCGHSEDAG ; VICSGPESSL ; 650: ALRLVNGGDR ; CQGRVEVLYR ; GSWGTVCDDS ; WDTNDANVVC ; RQLGCGWATS ; 700: APGNARFGQG ; SGPIVLDDVR ; CSGHESYLWS ; CPNNGWLSHN ; CGHHEDAGVI ; 750: CSAAQSRSTP ; RPDTLSTITL ; PPSTVGSESS ; LTLRLVNGSD ; RCQGRVEVLY ; 800: RGSWGTVCDD ; SWDTNDANVV ; CRQLGCGWAT ; SAPGNARFGQ ; GSGPIVLDDV ; 850: RCSGHESYLW ; SCPHNGWLSH ; NCGHHEDAGV ; ICSVSQSRPT ; PSPDTWPTSH ; 900: ASTAGPESSL ; ALRLVNGGDR ; CQGRVEVLYR ; GSWGTVCDDS ; WDTSDANVVC ; 950: RQLGCGWATS ; APGNARFGQG ; SGPIVLDDVR ; CSGYESYLWS ; CPHNGWLSHN ; 1000: CQHSEDAGVI ; CSAAHSWSTP ; SPDTLPTITL ; PASTVGSESS ; LALRLVNGGD ; 1050: RCQGRVEVLY ; QGSWGTVCDD ; SWDTNDANVV ; CRQLGCGWAM ; SAPGNARFGQ ; 1100: GSGPIVLDDV ; RCSGHESYLW ; SCPHNGWLSH ; NCGHSEDAGV ; ICSASQSRPT ; 1150: PSPDTWPTSH ; ASTAGSESSL ; ALRLVNGGDR ; CQGRVEVLYR ; GSWGTVCDDY ; 1200: WDTNDANVVC ; RQLGCGWAMS ; APGNARFGQG ; SGPIVLDDVR ; CSGHESYLWS ; 1250: CPHNGWLSHN ; CGHHEDAGVI ; CSASQSQPTP ; SPDTWPTSHA ; STAGSESSLA ; 1300: LRLVNGGDRC ; QGRVEVLYRG ; SWGTVCDDYW ; DTNDANVVCR ; QLGCGWATSA ; 1350: PGNARFGQGS ; GPIVLDDVRC ; SGHESYLWSC ; PHNGWLSHNC ; GHHEDAGVIC ; 1400: SASQSQPTPS ; PDTWPTSHAS ; TAGSESSLAL ; RLVNGGDRCQ ; GRVEVLYRGS ; 1450: WGTVCDDYWD ; TNDANVVCRQ ; LGCGWATSAP ; GNARFGQGSG ; PIVLDDVRCS ; 1500: GHESYLWSCP ; HNGWLSHNCG ; HHEDAGVICS ; ASQSQPTPSP ; DTWPTSRAST ; 1550: AGSESTLALR ; LVNGGDRCRG ; RVEVLYQGSW ; GTVCDDYWDT ; NDANVVCRQL ; 1600: GCGWAMSAPG ; NAQFGQGSGP ; IVLDDVRCSG ; HESYLWSCPH ; NGWLSHNCGH ; 1650: HEDAGVICSA ; AQSQSTPRPD ; TWLTTNLPAL ; TVGSESSLAL ; RLVNGGDRCR ; 1700: GRVEVLYRGS ; WGTVCDDSWD ; TNDANVVCRQ ; LGCGWAMSAP ; GNARFGQGSG ; 1750: PIVLDDVRCS ; GNESYLWSCP ; HKGWLTHNCG ; HHEDAGVICS ; ATQINSTTTD ; 1800: WWHPTTTTTA ; RPSSNCGGFL ; FYASGTFSSP ; SYPAYYPNNA ; KCVWEIEVNS ; 1850: GYRINLGFSN ; LKLEAHHNCS ; FDYVEIFDGS ; LNSSLLLGKI ; CNDTRQIFTS ; 1900: SYNRMTIHFR ; SDISFQNTGF ; LAWYNSFPSD ; ATLRLVNLNS ; SYGLCAGRVE ; 1950: IYHGGTWGTV ; CDDSWTIQEA ; EVVCRQLGCG ; RAVSALGNAY ; FGSGSGPITL ; 2000: DDVECSGTES ; TLWQCRNRGW ; FSHNCNHRED ; AGVICSGNHL ; STPAPFLNIT ; 2050: RPNTDYSCGG ; FLSQPSGDFS ; SPFYPGNYPN ; NAKCVWDIEV ; QNNYRVTVIF ; 2100: RDVQLEGGCN ; YDYIEVFDGP ; YRSSPLIARV ; CDGARGSFTS ; SSNFMSIRFI ; 2150: SDHSITRRGF ; RAEYYSSPSN ; DSTNLLCLPN ; HMQASVSRSY ; LQSLGFSASD ; 2200: LVISTWNGYY ; ECRPQITPNL ; VIFTIPYSGC ; GTFKQADNDT ; IDYSNFLTAA ; 2250: VSGGIIKRRT ; DLRIHVSCRM ; LQNTWVDTMY ; IANDTIHVAN ; NTIQVEEVQY ; 2300: GNFDVNISFY ; TSSSFLYPVT ; SRPYYVDLNQ ; DLYVQAEILH ; SDAVLTLFVD ; 2350: TCVASPYSND ; FTSLTYDLIR ; SGCVRDDTYG ; PYSSPSLRIA ; RFRFRAFHFL ; 2400: NRFPSVYLRC ; KMVVCRAYDP ; SSRCYRGCVL ; RSKRDVGSYQ ; EKVDVVLGPI ; 2413: QLQTPPRREE ; EPR
Sequence Length	2413
String	Q9UGM3
Sub Unit	Interacts with LGALS3 (By similarity). Binds SFTPD and SPAR in a calcium-dependent manner. Binds to HIV-1 glycoprotein 120.

Uniprot	Q9UGM3
Gene Name	DMBT1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:1755
Unigene	Hs.279611

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BHE13803176	E15081h	96T	$736		Add to Cart

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