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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Cyclic AMP-dependent transcription factor ATF-2

SKU : BHE13801333

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E8848h
Alternative Names	Activating transcription factor 2 ; Cyclic AMP-responsive element-binding protein 2 ; CREB-2 ; HB16 ; Histone acetyltransferase ATF2 ; cAMP response element-binding protein CRE-BP1 ; CREB2 ; CREBP1
Categories	Elisa
Function	Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex.
Specificity	Natural and recombinant Human Cyclic AMP-dependent transcription factor ATF-2
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	ATF2_HUMAN
Method Type	Sandwich
Platform	PF00170
Protein Name	Cyclic AMP-dependent transcription factor ATF-2
Sensitivity	0.12ng/mL
Sequence	50: MKFKLHVNSA ; RQYKDLWNMS ; DDKPFLCTAP ; GCGQRFTNED ; HLAVHKHKHE ; 100: MTLKFGPARN ; DSVIVADQTP ; TPTRFLKNCE ; EVGLFNELAS ; PFENEFKKAS ; 150: EDDIKKMPLD ; LSPLATPIIR ; SKIEEPSVVE ; TTHQDSPLPH ; PESTTSDEKE ; 200: VPLAQTAQPT ; SAIVRPASLQ ; VPNVLLTSSD ; SSVIIQQAVP ; SPTSSTVITQ ; 250: APSSNRPIVP ; VPGPFPLLLH ; LPNGQTMPVA ; IPASITSSNV ; HVPAAVPLVR ; 300: PVTMVPSVPG ; IPGPSSPQPV ; QSEAKMRLKA ; ALTQQHPPVT ; NGDTVKGHGS ; 350: GLVRTQSEES ; RPQSLQQPAT ; STTETPASPA ; HTTPQTQSTS ; GRRRRAANED ; 400: PDEKRRKFLE ; RNRAAASRCR ; QKRKVWVQSL ; EKKAEDLSSL ; NGQLQSEVTL ; 450: LRNEVAQLKQ ; LLLAHKDCPV ; TAMQKKSGYH ; TADKDDSSED ; ISVPSSPHTE ; 500: AIQHSSVSTS ; NGVSSTSKAE ; AVATSVLTQM ; ADQSTEPALS ; QIVMAPSSQS ; 505: QPSGS
Sequence Length	505
String	P15336
Sub Unit	Binds DNA as a dimer and can form a homodimer in the absence of DNA. Can form a heterodimer with JUN. Interacts with SMAD3 and SMAD4. Binds through its N-terminal region to UTF1 which acts as a coactivator of ATF2 transcriptional activity.

Uniprot	P15336
Gene Name	ATF2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:1386
Unigene	Hs.592510

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801333	E8848h	96T	$736		Add to Cart

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