CCN family member 2 ; Hypertrophic chondrocyte-specific protein 24 ; Insulin-like growth factor-binding protein 8 ; IBP-8 ; CCN2 ; HCS24 ; IGFBP8
Categories
Elisa
Function
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.
Specificity
Natural and recombinant Human Connective tissue growth factor
Subcellular Location
Secreted extracellular space extracellular matrix Secreted