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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Complement C5

SKU : BHE13802989

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1969h
Alternative Names	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 ; CPAMD4
Categories	Elisa
Function	Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis).
Specificity	Natural and recombinant Human Complement C5
Subcellular Location	Secreted
Detection Range	0.156-10ng/ml
Entryname	CO5_HUMAN
Method Type	Sandwich
Platform	PF00207
Protein Name	Complement C5
Sensitivity	0.098ng/mL
Sequence	50: MGLLGILCFL ; IFLGKTWGQE ; QTYVISAPKI ; FRVGASENIV ; IQVYGYTEAF ; 100: DATISIKSYP ; DKKFSYSSGH ; VHLSSENKFQ ; NSAILTIQPK ; QLPGGQNPVS ; 150: YVYLEVVSKH ; FSKSKRMPIT ; YDNGFLFIHT ; DKPVYTPDQS ; VKVRVYSLND ; 200: DLKPAKRETV ; LTFIDPEGSE ; VDMVEEIDHI ; GIISFPDFKI ; PSNPRYGMWT ; 250: IKAKYKEDFS ; TTGTAYFEVK ; EYVLPHFSVS ; IEPEYNFIGY ; KNFKNFEITI ; 300: KARYFYNKVV ; TEADVYITFG ; IREDLKDDQK ; EMMQTAMQNT ; MLINGIAQVT ; 350: FDSETAVKEL ; SYYSLEDLNN ; KYLYIAVTVI ; ESTGGFSEEA ; EIPGIKYVLS ; 400: PYKLNLVATP ; LFLKPGIPYP ; IKVQVKDSLD ; QLVGGVPVTL ; NAQTIDVNQE ; 450: TSDLDPSKSV ; TRVDDGVASF ; VLNLPSGVTV ; LEFNVKTDAP ; DLPEENQARE ; 500: GYRAIAYSSL ; SQSYLYIDWT ; DNHKALLVGE ; HLNIIVTPKS ; PYIDKITHYN ; 550: YLILSKGKII ; HFGTREKFSD ; ASYQSINIPV ; TQNMVPSSRL ; LVYYIVTGEQ ; 600: TAELVSDSVW ; LNIEEKCGNQ ; LQVHLSPDAD ; AYSPGQTVSL ; NMATGMDSWV ; 650: ALAAVDSAVY ; GVQRGAKKPL ; ERVFQFLEKS ; DLGCGAGGGL ; NNANVFHLAG ; 700: LTFLTNANAD ; DSQENDEPCK ; EILRPRRTLQ ; KKIEEIAAKY ; KHSVVKKCCY ; 750: DGACVNNDET ; CEQRAARISL ; GPRCIKAFTE ; CCVVASQLRA ; NISHKDMQLG ; 800: RLHMKTLLPV ; SKPEIRSYFP ; ESWLWEVHLV ; PRRKQLQFAL ; PDSLTTWEIQ ; 850: GVGISNTGIC ; VADTVKAKVF ; KDVFLEMNIP ; YSVVRGEQIQ ; LKGTVYNYRT ; 900: SGMQFCVKMS ; AVEGICTSES ; PVIDHQGTKS ; SKCVRQKVEG ; SSSHLVTFTV ; 950: LPLEIGLHNI ; NFSLETWFGK ; EILVKTLRVV ; PEGVKRESYS ; GVTLDPRGIY ; 1000: GTISRRKEFP ; YRIPLDLVPK ; TEIKRILSVK ; GLLVGEILSA ; VLSQEGINIL ; 1050: THLPKGSAEA ; ELMSVVPVFY ; VFHYLETGNH ; WNIFHSDPLI ; EKQKLKKKLK ; 1100: EGMLSIMSYR ; NADYSYSVWK ; GGSASTWLTA ; FALRVLGQVN ; KYVEQNQNSI ; 1150: CNSLLWLVEN ; YQLDNGSFKE ; NSQYQPIKLQ ; GTLPVEAREN ; SLYLTAFTVI ; 1200: GIRKAFDICP ; LVKIDTALIK ; ADNFLLENTL ; PAQSTFTLAI ; SAYALSLGDK ; 1250: THPQFRSIVS ; ALKREALVKG ; NPPIYRFWKD ; NLQHKDSSVP ; NTGTARMVET ; 1300: TAYALLTSLN ; LKDINYVNPV ; IKWLSEEQRY ; GGGFYSTQDT ; INAIEGLTEY ; 1350: SLLVKQLRLS ; MDIDVSYKHK ; GALHNYKMTD ; KNFLGRPVEV ; LLNDDLIVST ; 1400: GFGSGLATVH ; VTTVVHKTST ; SEEVCSFYLK ; IDTQDIEASH ; YRGYGNSDYK ; 1450: RIVACASYKP ; SREESSSGSS ; HAVMDISLPT ; GISANEEDLK ; ALVEGVDQLF ; 1500: TDYQIKDGHV ; ILQLNSIPSS ; DFLCVRFRIF ; ELFEVGFLSP ; ATFTVYEYHR ; 1550: PDKQCTMFYS ; TSNIKIQKVC ; EGAACKCVEA ; DCGQMQEELD ; LTISAETRKQ ; 1600: TACKPEIAYA ; YKVSITSITV ; ENVFVKYKAT ; LLDIYKTGEA ; VAEKDSEITF ; 1650: IKKVTCTNAE ; LVKGRQYLIM ; GKEALQIKYN ; FSFRYIYPLD ; SLTWIEYWPR ; 1676: DTTCSSCQAF ; LANLDEFAED ; IFLNGC
Sequence Length	1676
String	P01031
Sub Unit	C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain). Interacts with tick complement inhibitor.

Uniprot	P01031
Gene Name	C5
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:727
Unigene	Hs.494997

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SKU	Supplier No.	Size	Your price	Quantity
BHE13802989	E1969h	96T	$736		Add to Cart

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