Activates ATF4-mediated transcription. Involved in ciliogenesis (By similarity). Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes.
Specificity
Natural and recombinant Human Centrosomal protein of 290 kDa
Subcellular Location
Cytoplasm cytoskeleton centrosome Nucleus Cell projection cilium Connecting cilium of photoreceptor cells, base of cilium in kidney intramedullary collecting duct cells.
Interacts with ATF4 via its N-terminal region. Part of selected centrosomal and microtubule-associated protein complexes. Interacts with CC2D2A. Interacts with IQCB1.