ELISA Kit for Human Caspase-3

Mfr.No.	E0626h
Alternative Names	Apopain ; Cysteine protease CPP32 ; CPP-32 ; Protein Yama ; SREBP cleavage activity 1 ; SCA-1 ; CPP32
Categories	Elisa
Function	Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp- ; -Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Specificity	Natural and recombinant Human Caspase-3
Subcellular Location	Cytoplasm
Detection Range	0.312-20ng/mL
Entryname	CASP3_HUMAN
Method Type	Sandwich
Platform	PF00656
Protein Name	Caspase-3
Sensitivity	0.078ng/mL
Sequence	50: MENTENSVDS ; KSIKNLEPKI ; IHGSESMDSG ; ISLDNSYKMD ; YPEMGLCIII ; 100: NNKNFHKSTG ; MTSRSGTDVD ; AANLRETFRN ; LKYEVRNKND ; LTREEIVELM ; 150: RDVSKEDHSK ; RSSFVCVLLS ; HGEEGIIFGT ; NGPVDLKKIT ; NFFRGDRCRS ; 200: LTGKPKLFII ; QACRGTELDC ; GIETDSGVDD ; DMACHKIPVE ; ADFLYAYSTA ; 250: PGYYSWRNSK ; DGSWFIQSLC ; AMLKQYADKL ; EFMHILTRVN ; RKVATEFESF ; 277: SFDATFHAKK ; QIPCIVSMLT ; KELYFYH
Sequence Length	277
String	P42574
Sub Unit	Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 17 kDa (p17) and a 12 kDa (p12) subunit.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801882	E0626h	96T	$536		Add to Cart