Involved in regulation of vitamin K-dependent carboxylation of multiple amino-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity.
Specificity
Natural and recombinant Human Calumenin
Subcellular Location
Endoplasmic reticulum lumen Secreted Melanosome Sarcoplasmic reticulum lumen Identified by mass spectrometry in melanosome fractions from stage I to stage IV.