ELISA Kit for Human Bcl2-associated agonist of cell death

Mfr.No.	E15040h
Alternative Names	Bcl-2-binding component 6 ; Bcl-2-like protein 8 ; Bcl2-L-8 ; Bcl-xL/Bcl-2-associated death promoter ; Bcl2 antagonist of cell death ; BBC6 ; BCL2L8
Categories	Elisa
Function	Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
Specificity	Natural and recombinant Human Bcl2-associated agonist of cell death
Subcellular Location	Mitochondrion outer membrane Cytoplasm Upon phosphorylation, locates to the cytoplasm.
Detection Range	0.156-10ng/mL
Entryname	BAD_HUMAN
Method Type	Sandwich
Platform	PF10514
Protein Name	Bcl2-associated agonist of cell death
Sensitivity	0.098ng/ml
Sequence	50: MFQIPEFEPS ; EQEDSSSAER ; GLGPSPAGDG ; PSGSGKHHRQ ; APGLLWDASH ; 100: QQEQPTSSSH ; HGGAGAVEIR ; SRHSSYPAGT ; EDDEGMGEEP ; SPFRGRSRSA ; 150: PPNLWAAQRY ; GRELRRMSDE ; FVDSFKKGLP ; RPKSAGTATQ ; MRQSSSWTRV ; 168: FQSWWDRNLG ; RGSSAPSQ
Sequence Length	168
String	Q92934
Sub Unit	Forms heterodimers with the anti-apoptotic proteins, Bcl-X(L), Bcl-2 and Bcl-W. Also binds protein S100A10 (By similarity). The Ser-75/Ser-99 phosphorylated form binds 14-3-3 proteins (By similarity). Interacts with PIM3.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801620	E15040h	96T	$736		Add to Cart