Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.
Specificity
Natural and recombinant Human BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
Subcellular Location
Mitochondrion Mitochondrion membrane Single-pass membrane protein Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria.