B-cell lymphoma 5 protein ; BCL-5 ; Protein LAZ-3 ; Zinc finger and BTB domain-containing protein 27 ; Zinc finger protein 51 ; BCL5 ; LAZ3 ; ZBTB27 ; ZNF51
Categories
Elisa
Function
Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.
Specificity
Natural and recombinant Human B-cell lymphoma 6 protein
Homodimer. Interacts (via BTB domain) with BCOR; the interaction is direct. Interacts (via BTB domain) with NCOR2; the interaction is direct. Interacts with ZBTB7 and BCL6B (By similarity). Interacts with the catalytic domain of HDAC9.