ATP-binding cassette transporter 9 ; ABC transporter 9 protein ; TAP-like protein ; TAPL ; KIAA1520
Categories
Elisa
Function
ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored.
Specificity
Natural and recombinant Human ATP-binding cassette sub-family B member 9
Subcellular Location
Lysosome membrane Multi-pass membrane protein May be located in membrane rafts.