C-type lectin domain family 4 member H2 ; Hepatic lectin H2 ; HL-2 ; CLEC4H2
Categories
Elisa
Function
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Specificity
Natural and recombinant Human Asialoglycoprotein receptor 2