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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Apoptotic protease-activating factor 1

SKU : BHE13801161

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1054h
Alternative Names	KIAA0413
Categories	Elisa
Function	Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.
Specificity	Natural and recombinant Human Apoptotic protease-activating factor 1
Subcellular Location	Cytoplasm
Entryname	APAF_HUMAN
Platform	PF00619
Protein Name	Apoptotic protease-activating factor 1
Sequence	50: MDAKARNCLL ; QHREALEKDI ; KTSYIMDHMI ; SDGFLTISEE ; EKVRNEPTQQ ; 100: QRAAMLIKMI ; LKKDNDSYVS ; FYNALLHEGY ; KDLAALLHDG ; IPVVSSSSGK ; 150: DSVSGITSYV ; RTVLCEGGVP ; QRPVVFVTRK ; KLVNAIQQKL ; SKLKGEPGWV ; 200: TIHGMAGCGK ; SVLAAEAVRD ; HSLLEGCFPG ; GVHWVSVGKQ ; DKSGLLMKLQ ; 250: NLCTRLDQDE ; SFSQRLPLNI ; EEAKDRLRIL ; MLRKHPRSLL ; ILDDVWDSWV ; 300: LKAFDSQCQI ; LLTTRDKSVT ; DSVMGPKYVV ; PVESSLGKEK ; GLEILSLFVN ; 350: MKKADLPEQA ; HSIIKECKGS ; PLVVSLIGAL ; LRDFPNRWEY ; YLKQLQNKQF ; 400: KRIRKSSSYD ; YEALDEAMSI ; SVEMLREDIK ; DYYTDLSILQ ; KDVKVPTKVL ; 450: CILWDMETEE ; VEDILQEFVN ; KSLLFCDRNG ; KSFRYYLHDL ; QVDFLTEKNC ; 500: SQLQDLHKKI ; ITQFQRYHQP ; HTLSPDQEDC ; MYWYNFLAYH ; MASAKMHKEL ; 550: CALMFSLDWI ; KAKTELVGPA ; HLIHEFVEYR ; HILDEKDCAV ; SENFQEFLSL ; 600: NGHLLGRQPF ; PNIVQLGLCE ; PETSEVYQQA ; KLQAKQEVDN ; GMLYLEWINK ; 650: KNITNLSRLV ; VRPHTDAVYH ; ACFSEDGQRI ; ASCGADKTLQ ; VFKAETGEKL ; 700: LEIKAHEDEV ; LCCAFSTDDR ; FIATCSVDKK ; VKIWNSMTGE ; LVHTYDEHSE ; 750: QVNCCHFTNS ; SHHLLLATGS ; SDCFLKLWDL ; NQKECRNTMF ; GHTNSVNHCR ; 800: FSPDDKLLAS ; CSADGTLKLW ; DATSANERKS ; INVKQFFLNL ; EDPQEDMEVI ; 850: VKCCSWSADG ; ARIMVAAKNK ; IFLFDIHTSG ; LLGEIHTGHH ; STIQYCDFSP ; 900: QNHLAVVALS ; QYCVELWNTD ; SRSKVADCRG ; HLSWVHGVMF ; SPDGSSFLTS ; 950: SDDQTIRLWE ; TKKVCKNSAV ; MLKQEVDVVF ; QENEVMVLAV ; DHIRRLQLIN ; 1000: GRTGQIDYLT ; EAQVSCCCLS ; PHLQYIAFGD ; ENGAIEILEL ; VNNRIFQSRF ; 1050: QHKKTVWHIQ ; FTADEKTLIS ; SSDDAEIQVW ; NWQLDKCIFL ; RGHQETVKDF ; 1100: RLLKNSRLLS ; WSFDGTVKVW ; NIITGNKEKD ; FVCHQGTVLS ; CDISHDATKF ; 1150: SSTSADKTAK ; IWSFDLLLPL ; HELRGHNGCV ; RCSAFSVDST ; LLATGDDNGE ; 1200: IRIWNVSNGE ; LLHLCAPLSE ; EGAATHGGWV ; TDLCFSPDGK ; MLISAGGYIK ; 1248: WWNVVTGESS ; QTFYTNGTNL ; KKIHVSPDFK ; TYVTVDNLGI ; LYILQTLE
Sequence Length	1248
String	O14727
Sub Unit	Monomer. Oligomerizes upon binding of cytochrome c and dATP. Oligomeric Apaf-1 and pro-caspase-9 bind to each other via their respective NH2-terminal CARD domains and consecutively mature caspase-9 is released from the complex. Pro-caspase-3 is recruited into the Apaf-1-pro-caspase-9 complex via interaction with pro-caspase-9. Interacts with APIP.

Uniprot	O14727
Gene Name	APAF1
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:317
Unigene	Hs.552567

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801161	E1054h	96T	$736		Add to Cart

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