ELISA Kit for Human Apoptosis-associated speck-like protein containing a CARD

Mfr.No.	E3198h
Alternative Names	Caspase recruitment domain-containing protein 5 ; PYD and CARD domain-containing protein ; Target of methylation-induced silencing 1 ; ASC ; CARD5 ; TMS1
Categories	Elisa
Function	Promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. May be a component of the inflammasome, a protein complex which also includes NALP2, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Specificity	Natural and recombinant Human Apoptosis-associated speck-like protein containing a CARD
Subcellular Location	Cytoplasm Upstream of caspase activation, a redistribution from the cytoplasm to the aggregates occurs. These appear as hollow, perinuclear spherical, ball-like structures.
Detection Range	0.156-10ng/mL
Entryname	ASC_HUMAN
Method Type	Sandwich
Platform	PF00619
Protein Name	Apoptosis-associated speck-like protein containing a CARD
Sensitivity	0.078ng/mL
Sequence	50: MGRARDAILD ; ALENLTAEEL ; KKFKLKLLSV ; PLREGYGRIP ; RGALLSMDAL ; 100: DLTDKLVSFY ; LETYGAELTA ; NVLRDMGLQE ; MAGQLQAATH ; QGSGAAPAGI ; 150: QAPPQSAAKP ; GLHFIDQHRA ; ALIARVTNVE ; WLLDALYGKV ; LTDEQYQAVR ; 195: AEPTNPSKMR ; KLFSFTPAWN ; WTCKDLLLQA ; LRESQSYLVE ; DLERS
Sequence Length	195
String	Q9ULZ3
Sub Unit	Forms complexes with other DAPIN domain-containing proteins. Interacts with CIAS1/PYPAF1 and PYDC1.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800788	E3198h	96T	$736		Add to Cart