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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Ankyrin-2

SKU : BHE13801042

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1633h
Alternative Names	Ankyrin-B ; Brain ankyrin ; Non-erythroid ankyrin
Categories	Elisa
Function	Attaches integral membrane proteins to cytoskeletal elements. Also binds to cytoskeletal proteins. Required for coordinate assembly of Na/Ca exchanger, Na/K ATPase and InsP3 receptor at sarcoplasmic reticulum sites in cardiomyocytes. Required for the coordinated expression of the Na/K ATPase, Na/Ca exchanger and beta-2-spectrin (SPTBN1) in the inner segment of rod photoreceptors. Required for expression and targeting of SPTBN1 in neonatal cardiomyocytes and for the regulation of neonatal cardiomyocyte contraction rate.
Specificity	Natural and recombinant Human Ankyrin-2
Subcellular Location	Cytoplasm cytoskeleton Membrane Cytoplasm myofibril sarcomere M line Apical cell membrane Cell membrane Expressed at the apical membrane of airway lung epithelial cells (By similarity). Localized to the plasma membrane of the inner segments of photoreceptors in retina. Colocalizes with SPTBN1 in a distict intracellular compartment of neonatal cardiomyocytes.
Detection Range	78-5000pg/mL
Entryname	ANK2_HUMAN
Method Type	Sandwich
Platform	PF00023
Protein Name	Ankyrin-2
Sensitivity	41.8pg/mL
Sequence	50: MMNEDAAQKS ; DSGEKFNGSS ; QRRKRPKKSD ; SNASFLRAAR ; AGNLDKVVEY ; 100: LKGGIDINTC ; NQNGLNALHL ; AAKEGHVGLV ; QELLGRGSSV ; DSATKKGNTA ; 150: LHIASLAGQA ; EVVKVLVKEG ; ANINAQSQNG ; FTPLYMAAQE ; NHIDVVKYLL ; 200: ENGANQSTAT ; EDGFTPLAVA ; LQQGHNQAVA ; ILLENDTKGK ; VRLPALHIAA ; 250: RKDDTKSAAL ; LLQNDHNADV ; QSKMMVNRTT ; ESGFTPLHIA ; AHYGNVNVAT ; 300: LLLNRGAAVD ; FTARNGITPL ; HVASKRGNTN ; MVKLLLDRGG ; QIDAKTRDGL ; 350: TPLHCAARSG ; HDQVVELLLE ; RGAPLLARTK ; NGLSPLHMAA ; QGDHVECVKH ; 400: LLQHKAPVDD ; VTLDYLTALH ; VAAHCGHYRV ; TKLLLDKRAN ; PNARALNGFT ; 450: PLHIACKKNR ; IKVMELLVKY ; GASIQAITES ; GLTPIHVAAF ; MGHLNIVLLL ; 500: LQNGASPDVT ; NIRGETALHM ; AARAGQVEVV ; RCLLRNGALV ; DARAREEQTP ; 550: LHIASRLGKT ; EIVQLLLQHM ; AHPDAATTNG ; YTPLHISARE ; GQVDVASVLL ; 600: EAGAAHSLAT ; KKGFTPLHVA ; AKYGSLDVAK ; LLLQRRAAAD ; SAGKNGLTPL ; 650: HVAAHYDNQK ; VALLLLEKGA ; SPHATAKNGY ; TPLHIAAKKN ; QMQIASTLLN ; 700: YGAETNIVTK ; QGVTPLHLAS ; QEGHTDMVTL ; LLDKGANIHM ; STKSGLTSLH ; 750: LAAQEDKVNV ; ADILTKHGAD ; QDAHTKLGYT ; PLIVACHYGN ; VKMVNFLLKQ ; 800: GANVNAKTKN ; GYTPLHQAAQ ; QGHTHIINVL ; LQHGAKPNAT ; TANGNTALAI ; 850: AKRLGYISVV ; DTLKVVTEEV ; TTTTTTITEK ; HKLNVPETMT ; EVLDVSDEEG ; 900: DDTMTGDGGE ; YLRPEDLKEL ; GDDSLPSSQF ; LDGMNYLRYS ; LEGGRSDSLR ; 950: SFSSDRSHTL ; SHASYLRDSA ; VMDDSVVIPS ; HQVSTLAKEA ; ERNSYRLSWG ; 1000: TENLDNVALS ; SSPIHSGFLV ; SFMVDARGGA ; MRGCRHNGLR ; IIIPPRKCTA ; 1050: PTRVTCRLVK ; RHRLATMPPM ; VEGEGLASRL ; IEVGPSGAQF ; LGPVIVEIPH ; 1100: FAALRGKERE ; LVVLRSENGD ; SWKEHFCDYT ; EDELNEILNG ; MDEVLDSPED ; 1150: LEKKRICRII ; TRDFPQYFAV ; VSRIKQDSNL ; IGPEGGVLSS ; TVVPQVQAVF ; 1200: PEGALTKRIR ; VGLQAQPMHS ; ELVKKILGNK ; ATFSPIVTLE ; PRRRKFHKPI ; 1250: TMTIPVPKAS ; SDVMLNGFGG ; DAPTLRLLCS ; ITGGTTPAQW ; EDITGTTPLT ; 1300: FVNECVSFTT ; NVSARFWLID ; CRQIQESVTF ; ASQVYREIIC ; VPYMAKFVVF ; 1350: AKSHDPIEAR ; LRCFCMTDDK ; VDKTLEQQEN ; FAEVARSRDV ; EVLEGKPIYV ; 1400: DCFGNLVPLT ; KSGQHHIFSF ; FAFKENRLPL ; FVKVRDTTQE ; PCGRLSFMKE ; 1450: PKSTRGLVHQ ; AICNLNITLP ; IYTKESESDQ ; EQEEEIDMTS ; EKNDETESTE ; 1500: TSVLKSHLVN ; EVPVLASPDL ; LSEVSEMKQD ; LIKMTAILTT ; DVSDKAGSIK ; 1550: VKELVKAAEE ; EPGEPFEIVE ; RVKEDLEKVN ; EILRSGTCTR ; DESSVQSSRS ; 1600: ERGLVEEEWV ; IVSDEEIEEA ; RQKAPLEITE ; YPCVEVRIDK ; EIKGKVEKDS ; 1650: TGLVNYLTDD ; LNTCVPLPKE ; QLQTVQDKAG ; KKCEALAVGR ; SSEKEGKDIP ; 1700: PDETQSTQKQ ; HKPSLGIKKP ; VRRKLKEKQK ; QKEEGLQASA ; EKAELKKGSS ; 1750: EESLGEDPGL ; APEPLPTVKA ; TSPLIEETPI ; GSIKDKVKAL ; QKRVEDEQKG ; 1800: RSKLPIRVKG ; KEDVPKKTTH ; RPHPAASPSL ; KSERHAPGSP ; SPKTERHSTL ; 1850: SSSAKTERHP ; PVSPSSKTEK ; HSPVSPSAKT ; ERHSPASSSS ; KTEKHSPVSP ; 1900: STKTERHSPV ; SSTKTERHPP ; VSPSGKTDKR ; PPVSPSGRTE ; KHPPVSPGRT ; 1950: EKRLPVSPSG ; RTDKHQPVST ; AGKTEKHLPV ; SPSGKTEKQP ; PVSPTSKTER ; 2000: IEETMSVREL ; MKAFQSGQDP ; SKHKTGLFEH ; KSAKQKQPQE ; KGKVRVEKEK ; 2050: GPILTQREAQ ; KTENQTIKRG ; QRLPVTGTAE ; SKRGVRVSSI ; GVKKEDAAGG ; 2100: KEKVLSHKIP ; EPVQSVPEEE ; SHRESEVPKE ; KMADEQGDMD ; LQISPDRKTS ; 2150: TDFSEVIKQE ; LEDNDKYQQF ; RLSEETEKAQ ; LHLDQVLTSP ; FNTTFPLDYM ; 2200: KDEFLPALSL ; QSGALDGSSE ; SLKNEGVAGS ; PCGSLMEGTP ; QISSEESYKH ; 2250: EGLAETPETS ; PESLSFSPKK ; SEEQTGETKE ; STKTETTTEI ; RSEKEHPTTK ; 2300: DITGGSEERG ; ATVTEDSETS ; TESFQKEATL ; GSPKDTSPKR ; QDDCTGSCSV ; 2350: ALAKETPTGL ; TEEAACDEGQ ; RTFGSSAHKT ; QTDSEVQEST ; ATSDETKALP ; 2400: LPEASVKTDT ; GTESKPQGVI ; RSPQGLELAL ; PSRDSEVLSA ; VADDSLAVSH ; 2450: KDSLEASPVL ; EDNSSHKTPD ; SLEPSPLKES ; PCRDSLESSP ; VEPKMKAGIF ; 2500: PSHFPLPAAV ; AKTELLTEVA ; SVRSRLLRDP ; DGSAEDDSLE ; QTSLMESSGK ; 2550: SPLSPDTPSS ; EEVSYEVTPK ; TTDVSTPKPA ; VIHECAEEDD ; SENGEKKRFT ; 2600: PEEEMFKMVT ; KIKMFDELEQ ; EAKQKRDYKK ; EPKQEESSSS ; SDPDADCSVD ; 2650: VDEPKHTGSG ; EDESGVPVLV ; TSESRKVSSS ; SESEPELAQL ; KKGADSGLLP ; 2700: EPVIRVQPPS ; PLPSSMDSNS ; SPEEVQFQPV ; VSKQYTFKMN ; EDTQEEPGKS ; 2750: EEEKDSESHL ; AEDRHAVSTE ; AEDRSYDKLN ; RDTDQPKICD ; GHGCEAMSPS ; 2800: SSAAPVSSGL ; QSPTGDDVDE ; QPVIYKESLA ; LQGTHEKDTE ; GEELDVSRAE ; 2850: SPQADCPSES ; FSSSSSLPHC ; LVSEGKELDE ; DISATSSIQK ; TEVTKTDETF ; 2900: ENLPKDCPSQ ; DSSITTQTDR ; FSMDVPVSDL ; AENDEIYDPQ ; ITSPYENVPS ; 2950: QSFFSSEESK ; TQTDANHTTS ; FHSSEVYSVT ; ITSPVEDVVV ; ASSSSGTVLS ; 3000: KESNFEGQDI ; KMESQQESTL ; WEMQSDSVSS ; SFEPTMSATT ; TVVGEQISKV ; 3050: IITKTDVDSD ; SWSEIREDDE ; AFEARVKEEE ; QKIFGLMVDR ; QSQGTTPDTT ; 3100: PARTPTEEGT ; PTSEQNPFLF ; QEGKLFEMTR ; SGAIDMTKRS ; YADESFHFFQ ; 3150: IGQESREETL ; SEDVKEGATG ; ADPLPLETSA ; ESLALSESKE ; TVDDEADLLP ; 3200: DDVSEEVEEI ; PASDAQLNSQ ; MGISASTETP ; TKEAVSVGTK ; DLPTVQTGDI ; 3250: PPLSGVKQIS ; CPDSSEPAVQ ; VQLDFSTLTR ; SVYSDRGDDS ; PDSSPEEQKS ; 3300: VIEIPTAPME ; NVPFTESKSK ; IPVRTMPTST ; PAPPSAEYES ; SVSEDFLSSV ; 3350: DEENKADEAK ; PKSKLPVKVP ; LQRVEQQLSD ; LDTSVQKTVA ; PQGQDMASIA ; 3400: PDNRSKSESD ; ASSLDSKTKC ; PVKTRSYTET ; ETESRERAEE ; LELESEEGAT ; 3450: RPKILTSRLP ; VKSRSTTSSC ; RGGTSPTKES ; KEHFFDLYRN ; SIEFFEEISD ; 3500: EASKLVDRLT ; QSEREQEIVS ; DDESSSALEV ; SVIENLPPVE ; TEHSVPEDIF ; 3550: DTRPIWDESI ; ETLIERIPDE ; NGHDHAEDPQ ; DEQERIEERL ; AYIADHLGFS ; 3600: WTELARELDF ; TEEQIHQIRI ; ENPNSLQDQS ; HALLKYWLER ; DGKHATDTNL ; 3650: VECLTKINRM ; DIVHLMETNT ; EPLQERISHS ; YAEIEQTITL ; DHSEGFSVLQ ; 3700: EELCTAQHKQ ; KEEQAVSKES ; ETCDHPPIVS ; EEDISVGYST ; FQDGVPKTEG ; 3750: DSSATALFPQ ; THKEQVQQDF ; SGKMQDLPEE ; SSLEYQQEYF ; VTTPGTETSE ; 3800: TQKAMIVPSS ; PSKTPEEVST ; PAEEEKLYLQ ; TPTSSERGGS ; PIIQEPEEPS ; 3850: EHREESSPRK ; TSLVIVESAD ; NQPETCERLD ; EDAAFEKGDD ; MPEIPPETVT ; 3900: EEEYIDEHGH ; TVVKKVTRKI ; IRRYVSSEGT ; EKEEIMVQGM ; PQEPVNIEEG ; 3924: DGYSKVIKRV ; VLKSDTEQSE ; DNNE
Sequence Length	3924
String	Q01484
Sub Unit	Interacts with RHBG and SPTBN1.

Uniprot	Q01484
Gene Name	ANK2
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:287
Unigene	Hs.620557

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