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Home / Assay Kits / ELISA Kits

ELISA Kit for Human Aminopeptidase N

SKU : BHE13800656

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9154h
Alternative Names	Alanyl aminopeptidase ; Aminopeptidase M ; AP-M ; Microsomal aminopeptidase ; Myeloid plasma membrane glycoprotein CD13 ; gp150 ; CD13 ; APN ; CD13 ; PEPN
Categories	Elisa
Function	Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types including small intestinal and tubular epithelial cells, macrophages, granulocytes and synaptic membranes from the CNS. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection.
Specificity	Natural and recombinant Human Aminopeptidase N
Subcellular Location	Cell membrane Single-pass type II membrane protein Cytoplasm cytosol A soluble form has also been detected.
Detection Range	0.156-10ng/mL
Entryname	AMPN_HUMAN
Method Type	Sandwich
Platform	PF11838
Protein Name	Aminopeptidase N
Sensitivity	0.085ng/mL
Sequence	50: MAKGFYISKS ; LGILGILLGV ; AAVCTIIALS ; VVYSQEKNKN ; ANSSPVASTT ; 100: PSASATTNPA ; SATTLDQSKA ; WNRYRLPNTL ; KPDSYRVTLR ; PYLTPNDRGL ; 150: YVFKGSSTVR ; FTCKEATDVI ; IIHSKKLNYT ; LSQGHRVVLR ; GVGGSQPPDI ; 200: DKTELVEPTE ; YLVVHLKGSL ; VKDSQYEMDS ; EFEGELADDL ; AGFYRSEYME ; 250: GNVRKVVATT ; QMQAADARKS ; FPCFDEPAMK ; AEFNITLIHP ; KDLTALSNML ; 300: PKGPSTPLPE ; DPNWNVTEFH ; TTPKMSTYLL ; AFIVSEFDYV ; EKQASNGVLI ; 350: RIWARPSAIA ; AGHGDYALNV ; TGPILNFFAG ; HYDTPYPLPK ; SDQIGLPDFN ; 400: AGAMENWGLV ; TYRENSLLFD ; PLSSSSSNKE ; RVVTVIAHEL ; AHQWFGNLVT ; 450: IEWWNDLWLN ; EGFASYVEYL ; GADYAEPTWN ; LKDLMVLNDV ; YRVMAVDALA ; 500: SSHPLSTPAS ; EINTPAQISE ; LFDAISYSKG ; ASVLRMLSSF ; LSEDVFKQGL ; 550: ASYLHTFAYQ ; NTIYLNLWDH ; LQEAVNNRSI ; QLPTTVRDIM ; NRWTLQMGFP ; 600: VITVDTSTGT ; LSQEHFLLDP ; DSNVTRPSEF ; NYVWIVPITS ; IRDGRQQQDY ; 650: WLIDVRAQND ; LFSTSGNEWV ; LLNLNVTGYY ; RVNYDEENWR ; KIQTQLQRDH ; 700: SAIPVINRAQ ; IINDAFNLAS ; AHKVPVTLAL ; NNTLFLIEER ; QYMPWEAALS ; 750: SLSYFKLMFD ; RSEVYGPMKN ; YLKKQVTPLF ; IHFRNNTNNW ; REIPENLMDQ ; 800: YSEVNAISTA ; CSNGVPECEE ; MVSGLFKQWM ; ENPNNNPIHP ; NLRSTVYCNA ; 850: IAQGGEEEWD ; FAWEQFRNAT ; LVNEADKLRA ; ALACSKELWI ; LNRYLSYTLN ; 900: PDLIRKQDAT ; STIISITNNV ; IGQGLVWDFV ; QSNWKKLFND ; YGGGSFSFSN ; 950: LIQAVTRRFS ; TEYELQQLEQ ; FKKDNEETGF ; GSGTRALEQA ; LEKTKANIKW ; 967: VKENKEVVLQ ; WFTENSK
Sequence Length	967
String	P15144
Sub Unit	Homodimer. Interacts with the S1 domain of HCoV-229E spike protein.

Uniprot	P15144
Gene Name	ANPEP
Immunogen Species	Homo Sapiens (Human)
Kegg	hsa:290
Unigene	Hs.1239

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800656	E9154h	96T	$736		Add to Cart

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